NIT2

Gene Symbol	NIT2
Entrez Gene	56954
Alt Symbol	HEL-S-8a
Species	Human
Gene Type	protein-coding
Description	nitrilase family, member 2
Other Description	Nit protein 2|epididymis secretory sperm binding protein Li 8a|nitrilase homolog 2|omega-amidase NIT2
Swissprots	Q9NQR4 B2R9A3 Q8WUF0 D3DN47
Accessions	EAW79824 EAW79825 Q9NQR4 AF260334 AAG44665 AF284574 AAF87103 AK225979 AK294010 BAG57372 AK295835 BAH12195 AK313704 BAG36450 BC020620 AAH20620 BC107890 AAI07891 BM748852 DB466042 DQ893135 ABM84061 DQ896416 ABM87415 FJ224326 ACI46018 NM_020202 NP_064587
Function	Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. {ECO:0000269|PubMed:17488281, ECO:0000269|PubMed:19595734}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17488281}.
Tissue Specificity	Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon. {ECO:0000269|PubMed:14528910, ECO:0000269|PubMed:17488281}.
Top Pathways	Alanine, aspartate and glutamate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NIT2 - MBS1271817 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC020620

Human NIT2 ORF Clone (BC020620) - CDCS415026 from Creative biogene Species Human Accession Q9NQR4

Human NIT2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG23517-NF from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, N-His tag - HG23517-NH from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG23517-NY from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone in cloning vector - HG23517-U from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid - HG23517-UT from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG23517-ACG from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG23517-ACR from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG23517-ANG from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG23517-ANR from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG23517-CF from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, C-His tag - HG23517-CH from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG23517-CM from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG23517-NM from Sino Biological Species Human

Human NIT2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG23517-CY from Sino Biological Species Human

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