NIT2

Gene Symbol NIT2
Entrez Gene 56954
Alt Symbol HEL-S-8a
Species Human
Gene Type protein-coding
Description nitrilase family, member 2
Other Description Nit protein 2|epididymis secretory sperm binding protein Li 8a|nitrilase homolog 2|omega-amidase NIT2
Swissprots Q9NQR4 B2R9A3 Q8WUF0 D3DN47
Accessions EAW79824 EAW79825 Q9NQR4 AF260334 AAG44665 AF284574 AAF87103 AK225979 AK294010 BAG57372 AK295835 BAH12195 AK313704 BAG36450 BC020620 AAH20620 BC107890 AAI07891 BM748852 DB466042 DQ893135 ABM84061 DQ896416 ABM87415 FJ224326 ACI46018 NM_020202 NP_064587
Function Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. {ECO:0000269|PubMed:17488281, ECO:0000269|PubMed:19595734}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17488281}.
Tissue Specificity Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon. {ECO:0000269|PubMed:14528910, ECO:0000269|PubMed:17488281}.
Top Pathways Alanine, aspartate and glutamate metabolism

NIT2 CRISPR/Cas9 KO Plasmid (h) - sc-412737 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 HDR Plasmid (h) - sc-412737-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 Double Nickase Plasmid (h) - sc-412737-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 Double Nickase Plasmid (h2) - sc-412737-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 CRISPR Activation Plasmid (h) - sc-412737-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 CRISPR Activation Plasmid (h2) - sc-412737-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 Lentiviral Activation Particles (h) - sc-412737-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 Lentiviral Activation Particles (h2) - sc-412737-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT2 siRNA (h) - sc-78047 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIT2 shRNA Plasmid (h) - sc-78047-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIT2 shRNA (h) Lentiviral Particles - sc-78047-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15312 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15312 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NIT2 siRNA (Human) - CRJ1253 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NIT2 (NM_020202.4) - SHH352608 from Creative biogene

Category siRNA
Species Reactivities Human

Human NIT2 siRNA - orb271754 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NIT2 shRNA Plasmid (Human) - CHJ1253 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NIT2 miRNA 3'UTR clone - MiUTR3H-15588 from Creative biogene

Species Reactivities Human
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