NIT2

Gene Symbol	NIT2
Entrez Gene	56954
Alt Symbol	HEL-S-8a
Species	Human
Gene Type	protein-coding
Description	nitrilase family, member 2
Other Description	Nit protein 2|epididymis secretory sperm binding protein Li 8a|nitrilase homolog 2|omega-amidase NIT2
Swissprots	Q9NQR4 B2R9A3 Q8WUF0 D3DN47
Accessions	EAW79824 EAW79825 Q9NQR4 AF260334 AAG44665 AF284574 AAF87103 AK225979 AK294010 BAG57372 AK295835 BAH12195 AK313704 BAG36450 BC020620 AAH20620 BC107890 AAI07891 BM748852 DB466042 DQ893135 ABM84061 DQ896416 ABM87415 FJ224326 ACI46018 NM_020202 NP_064587
Function	Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. {ECO:0000269|PubMed:17488281, ECO:0000269|PubMed:19595734}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17488281}.
Tissue Specificity	Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon. {ECO:0000269|PubMed:14528910, ECO:0000269|PubMed:17488281}.
Top Pathways	Alanine, aspartate and glutamate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NIT2 full length protein - ab102690 from Abcam Category Protein Source E. coli Species Human

Human NIT2 full length protein - ab88137 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

NIT2 Antibody Blocking Peptide - LS-E16881 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NIT2 Recombinant Protein - H00056954-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NIT2 Protein - NBP1-50903 from Novus Biologicals Category Protein Prices $369.00 Sizes 50 µg

NIT2 Protein (OPPA02557) - OPPA02557 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human NIT2 protein - orb168927 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

NIT2 Blocking Peptide - 33R-9421 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NIT2 protein (His tag) - 80R-1580 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

NIT2 (1-276, His-tag) - AR09759PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

NIT2 (1-276, His-tag) - AR09759PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

NIT2 - H00056954-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NIT2 - H00056954-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Nitrilase Family Member 2, Human Recombinant - 228-12192-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

NIT2, 1-276aa, Human, His tag, E.coli - 01-P0819 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

NIT2 fusion protein - Ag9889 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NIT2 fusion protein - ag9756 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NIT2 Human - ENPS-046 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Nitrilase Family Member 2 - BP000719-ENZ-039 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

NIT2 Human Protein - GWB-BSP255 from Genway Biotech Category Protein Prices $75.00, $165.00, $5,700.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

NIT2, 1-276aa, Recombinant Protein - GWB-P1219J from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human NIT2 - NIT2-26962TH from Creative Biomart Category Protein

Recombinant Human NIT2, His-tagged - NIT2-26965TH from Creative Biomart Category Protein Source E. coli

Recombinant Human NIT2, His-tagged - NIT2-1297H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Nitrilase Family, Member 2, His-tagged - NIT2-3365H from Creative Biomart Category Protein Source E.coli.

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