FFAR4

Gene Symbol	FFAR4
Entrez Gene	338557
Alt Symbol	BMIQ10, GPR120, GPR129, GT01, O3FAR1, PGR4
Species	Human
Gene Type	protein-coding
Description	free fatty acid receptor 4
Other Description	G-protein coupled receptor 120|G-protein coupled receptor 129|G-protein coupled receptor GT01|G-protein coupled receptor PGR4|omega-3 fatty acid receptor 1
Swissprots	Q5VY26 Q495H1 Q5NUL3 Q86SM7 Q7Z605 Q5VY25
Accessions	EAW50069 EAW50070 Q5NUL3 AB115768 BAD83368 AI469384 AI732606 AK301525 BAG63028 AY255573 AAO85085 AY288417 AAP72126 BC101175 AAI01176 BM757151 BX647721 DA986310 XM_011539746 XP_011538048 NM_001195755 NP_001182684 NM_181745 NP_859529
Function	Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage- induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation. {ECO:0000269|PubMed:15619630}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Colocalized with ARRB2 following DHA treatment. {ECO:0000250}.
Tissue Specificity	Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas. {ECO:0000269|PubMed:15619630, ECO:0000269|PubMed:17250804}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human O3FAR1 / GPR120 ELISA Kit (Sandwich ELISA) - LS-F8453 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.252 ng/ml Range 0.625-40 ng/ml

Mouse O3FAR1 / GPR120 ELISA Kit (Sandwich ELISA) - LS-F8688 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.123 ng/ml Range 0.625-40 ng/ml

Human O3FAR1 / GPR120 ELISA Kit (Sandwich ELISA) - LS-F12204 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.625-40 ng/ml

Mouse O3FAR1 / GPR120 ELISA Kit (Sandwich ELISA) - LS-F12203 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 0.625-40 ng/ml

Human GPR120 ELISA Kit - abx151717 from Abbexa Category ELISA Kit Sensitivity 0.224 ng/ml Range 0.625 ng/ml - 40 ng/ml

G Protein Coupled Receptor 120 (GPR120), Human, ELISA Kit - SEG697Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.224ng/mL Range 0.625-40ng/mL

G Protein Coupled Receptor 120, GPR120, Human, ELISA Kit - E-EL-H1283 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.375 Range 0.625-40ng/mL

Omega-3 fatty acid receptor 1 (GPR120), Human, ELISA Kit - CSB-EL009743HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

Omega-3 fatty acid receptor 1, O3FAR1, Human, ELISA Kit - E12801h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

G Protein Coupled Receptor 120, GPR120, Rabbit, ELISA Kit - E-EL-RB1508 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

G Protein Coupled Receptor 120, GPR120, Chicken, ELISA Kit - E-EL-Ch2173 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

G Protein Coupled Receptor 120, GPR120, Porcine, ELISA Kit - E-EL-P0280 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

G Protein Coupled Receptor 120, GPR120, Sheep, ELISA Kit - E-EL-S0678 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

G Protein Coupled Receptor 120, GPR120, Guinea Pig, ELISA Kit - E-EL-GP1201 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

G Protein Coupled Receptor 120, GPR120, Monkey, ELISA Kit - E-EL-MK0630 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human GPR120(G Protein Coupled Receptor 120) ELISA Kit - E-EL-H1283 from Elabscience Category ELISA Kit Sensitivity 0.38 ng/mL Range 0.63—40 ng/mL

Human GPR120 (G Protein Coupled Receptor 120) CLIA Kit - E-CL-H0835 from Elabscience Category CLIA Kit Sensitivity 0.09 ng/mL Range Average Recovery (%)

G Protein Coupled Receptor 120, ELISA Kit - MBS088576 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

G Protein Coupled Receptor 120, ELISA Kit - MBS055814 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

G Protein Coupled Receptor 120, ELISA Kit - MBS063752 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

G Protein Coupled Receptor 120, ELISA Kit - MBS083479 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

G Protein Coupled Receptor 120, ELISA Kit - MBS094521 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

G Protein Coupled Receptor 120, ELISA Kit - MBS102225 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/ml. Range 3.12 ng/ml - 100 ng/ml.

G Protein Coupled Receptor 120, ELISA Kit - MBS090215 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

G Protein Coupled Receptor 120, ELISA Kit - MBS081528 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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