FFAR4

Gene Symbol	FFAR4
Entrez Gene	338557
Alt Symbol	BMIQ10, GPR120, GPR129, GT01, O3FAR1, PGR4
Species	Human
Gene Type	protein-coding
Description	free fatty acid receptor 4
Other Description	G-protein coupled receptor 120|G-protein coupled receptor 129|G-protein coupled receptor GT01|G-protein coupled receptor PGR4|omega-3 fatty acid receptor 1
Swissprots	Q5VY26 Q495H1 Q5NUL3 Q86SM7 Q7Z605 Q5VY25
Accessions	EAW50069 EAW50070 Q5NUL3 AB115768 BAD83368 AI469384 AI732606 AK301525 BAG63028 AY255573 AAO85085 AY288417 AAP72126 BC101175 AAI01176 BM757151 BX647721 DA986310 XM_011539746 XP_011538048 NM_001195755 NP_001182684 NM_181745 NP_859529
Function	Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage- induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation. {ECO:0000269|PubMed:15619630}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Colocalized with ARRB2 following DHA treatment. {ECO:0000250}.
Tissue Specificity	Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas. {ECO:0000269|PubMed:15619630, ECO:0000269|PubMed:17250804}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

O3FAR1 / GPR120 Antibody Blocking Peptide - LS-E4660 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

O3FAR1 / GPR120 Antibody Blocking Peptide - LS-E28465 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

O3FAR1 / GPR120 Antibody Blocking Peptide - LS-E28463 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

O3FAR1 / GPR120 Antibody Blocking Peptide - LS-E28464 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

O3FAR1 / GPR120 Antibody Blocking Peptide - LS-E28466 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

O3FAR1 / GPR120 Antibody Blocking Peptide - LS-E26834 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FFAR4/GPR120 Peptide - NLS2004PEP from Novus Biologicals Category Peptide Prices $229.00 Sizes 50 µg Species Human

GPR120-Antibody-Center-Blocking-Peptide - BP17024c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPR120 peptide - GTX30752 from GeneTex Category Peptide Prices $179.00 Sizes 25 μg

GPR120 blocking peptide - GTX88579-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

GPCR GPR120 Peptide - AC21-1666-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GPR120 Peptide - 46-950P from ProSci Category Peptide

GPR120 fusion protein - ag17283 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant G Protein Coupled Receptor 120 (GPR120) - RPG697Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant G Protein Coupled Receptor 120 (GPR120) - RPG697Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant G Protein Coupled Receptor 120 (GPR120) - RPG697Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

GPR120 (V259) Peptide - BS2778P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant G Protein Coupled Receptor 120 (GPR120) - RPG697Hu01 from Cloud-clone Category Protein Source E.coli Species Human

GPR120 Blocking Peptide - abx161692 from Abbexa Category Peptide Species Human

GPR120, Peptide - MBS425620 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

FFAR4/GPR120 Recombinant Protein Antigen - NBP1-89739PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GPR120 fusion protein - ag20718 from Proteintech Group Category Protein Species Human

O3FAR1 Peptide, Human - M34GP10781H from Creative Peptides Category Peptide Source Synthetic. Species Human

GPR120 Blocking Peptide - CBP4481 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

GPR120 Blocking Peptide - orb392826 from Biorbyt Category Peptide Prices $238.00, $476.00 Sizes 1 mg, 5 mg Species Human

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