DHFRL1

Gene Symbol DHFRL1
Entrez Gene 200895
Alt Symbol DHFRP4
Species Human
Gene Type protein-coding
Description dihydrofolate reductase-like 1
Other Description dihydrofolate reductase pseudogene 4|dihydrofolate reductase, mitochondrial|dihydrofolate reductase-like protein 1
Swissprots Q6P4I9 D3DN30 Q86XF0
Accessions EAW79895 EAW79896 Q86XF0 AK122674 BAG53658 AL832912 CAH10617 AW104373 BC045541 AAH45541 BC063379 AAH63379 HQ447989 ADQ32471 XM_011512537 XP_011510839 NM_001195643 NP_001182572 NM_176815 NP_789785
Function Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. {ECO:0000269|PubMed:21876184, ECO:0000269|PubMed:21876188}.
Subcellular Location Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Tissue Specificity Expressed in numerous cell lines. {ECO:0000269|PubMed:21876184}.
Top Pathways Folate biosynthesis, One carbon pool by folate

Human DHFRL1 Gene cDNA Clone - orb142852 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

Human-DHFRL1-cDNA-Clone - DC07569 from Abgent, a WuXi AppTec company

Prices $252.45
Sizes 10 µg
Species Human
Accession BC045541

DHFRL1 - MBS1266484 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC045541

Human DHFRL1 ORF Clone (BC045541) - CDCS409335 from Creative biogene

Species Human
Accession Q86XF0

Human DHFRL1 ORF clone (BC045541) - CDCB158417 from Creative biogene

Species Human
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