DHFRL1

Gene Symbol	DHFRL1
Entrez Gene	200895
Alt Symbol	DHFRP4
Species	Human
Gene Type	protein-coding
Description	dihydrofolate reductase-like 1
Other Description	dihydrofolate reductase pseudogene 4|dihydrofolate reductase, mitochondrial|dihydrofolate reductase-like protein 1
Swissprots	Q6P4I9 D3DN30 Q86XF0
Accessions	EAW79895 EAW79896 Q86XF0 AK122674 BAG53658 AL832912 CAH10617 AW104373 BC045541 AAH45541 BC063379 AAH63379 HQ447989 ADQ32471 XM_011512537 XP_011510839 NM_001195643 NP_001182572 NM_176815 NP_789785
Function	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. {ECO:0000269|PubMed:21876184, ECO:0000269|PubMed:21876188}.
Subcellular Location	Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Tissue Specificity	Expressed in numerous cell lines. {ECO:0000269|PubMed:21876184}.
Top Pathways	Folate biosynthesis, One carbon pool by folate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DHFRL1 full length protein - ab165872 from Abcam Category Protein Source Wheat germ Species Human

DHFRL1 Antibody Blocking Peptide - LS-E2386 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DHFRL1 Antibody Blocking Peptide - LS-E19256 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DHFRL1 Protein - H00200895-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DHFRL1-Antibody-Center-Blocking-peptide - BP13364c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DHFRL1 Blocking Peptide - 33R-7973 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DHFRL1 / DHFRP4 - H00200895-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DHFRL1 / DHFRP4 - H00200895-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DHFRL1 fusion protein - ag10537 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Dihydrofolate reductase, mitochondrial(DHFRL1) - CSB-YP773052HU CSB-EP773052HU CSB-BP773052HU CSB-MP773052HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DHFRL1 / DHFRP4 - TP308452 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DHFRL1 Protein - NBP2-33268PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

DHFRL1 Peptide, Human - M34GP04266H from Creative Peptides Category Peptide Source Synthetic. Species Human

Dihydrofolate reductase, mitochondrial (DHFRL1), Recombinant Protein - MBS1428723 from MyBioSource Category Protein Prices $935.00, $935.00, $1,155.00, $1,155.00, $1,395.00, $1,395.00, $1,850.00, $1,850.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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