DHFRL1

Gene Symbol DHFRL1
Entrez Gene 200895
Alt Symbol DHFRP4
Species Human
Gene Type protein-coding
Description dihydrofolate reductase-like 1
Other Description dihydrofolate reductase pseudogene 4|dihydrofolate reductase, mitochondrial|dihydrofolate reductase-like protein 1
Swissprots Q6P4I9 D3DN30 Q86XF0
Accessions EAW79895 EAW79896 Q86XF0 AK122674 BAG53658 AL832912 CAH10617 AW104373 BC045541 AAH45541 BC063379 AAH63379 HQ447989 ADQ32471 XM_011512537 XP_011510839 NM_001195643 NP_001182572 NM_176815 NP_789785
Function Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. {ECO:0000269|PubMed:21876184, ECO:0000269|PubMed:21876188}.
Subcellular Location Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Tissue Specificity Expressed in numerous cell lines. {ECO:0000269|PubMed:21876184}.
Top Pathways Folate biosynthesis, One carbon pool by folate

DHFRL1 CRISPR/Cas9 KO Plasmid (h) - sc-416991 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFRL1 HDR Plasmid (h) - sc-416991-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFR Double Nickase Plasmid (h) - sc-416991-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFRL1 Double Nickase Plasmid (h2) - sc-416991-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFR CRISPR Activation Plasmid (h) - sc-416991-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFRL1 CRISPR Activation Plasmid (h2) - sc-416991-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFR Lentiviral Activation Particles (h) - sc-416991-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DHFRL1 Lentiviral Activation Particles (h2) - sc-416991-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MISSION® esiRNA - EHU108971 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7194 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7194 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DHFRL1 siRNA (Human) - CRJ6266 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DHFRL1 - MBS8226931 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DHFRL1 (NM_176815.4) - SHH277625 from Creative biogene

Category siRNA
Species Reactivities Human

Human DHFRL1 siRNA - orb276767 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DHFRL1 shRNA Plasmid (Human) - CHJ6266 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DHFRL1 miRNA 3'UTR clone - MiUTR4H-TG02709 from Creative biogene

Species Reactivities Human
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