DYRK1B

Gene Symbol DYRK1B
Entrez Gene 9149
Alt Symbol AOMS3, MIRK
Species Human
Gene Type protein-coding
Description dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Other Description dual specificity tyrosine-phosphorylation-regulated kinase 1B|minibrain-related kinase|mirk protein kinase
Swissprots O75789 Q9Y463 O75258 O75788
Accessions AAC28914 EAW56916 EAW56917 EAW56918 EAW56919 EAW56920 EAW56921 EAW56922 EAW56923 EAW56924 Q9Y463 AF205861 AAF15893 AK074971 BAG52042 AK302127 BAG63504 BC009688 BC018751 AAH18751 BC025291 AAH25291 BI964831 BQ446787 DQ892536 ABM83462 DQ895747 ABM86673 HY024135 Y17999 CAA76989 XM_005259395 XP_005259452 XM_005259398 XP_005259455 XM_011527469 XP_011525771 XM_011527470 XP_011525772 XM_011548813 XP_011547115 XM_011548814 XP_011547116 XM_011548815 XP_011547117 XM_011548816 XP_011547118 NM_004714 NP_004705 NM_006483 NP_006474 NM_006484 NP_006475
Function Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC). {ECO:0000269|PubMed:10910078, ECO:0000269|PubMed:11980910, ECO:0000269|PubMed:14500717, ECO:0000269|PubMed:24827035}.
Subcellular Location Nucleus.
Tissue Specificity Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. {ECO:0000269|PubMed:10910078}.

DYRK1B (D40D1) Rabbit mAb - 5672 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D40D1
Western blot analysis of extracts from various cell lines and tissues using DYRK1B (D40D1) Rabbit mAb.

DYRK1B Antibody - 2703 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines and rat testes using DYRK1B Antibody.

Dyrk1B (B-9) - sc-377137 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dyrk1B (B-9): sc-377137. Western blot analysis of Dyrk1B expression in non-transfected: sc-117752 (A) and human Dyrk1B transfected: sc-158463 (B) 293T whole cell lysates.

Dyrk1B (H-6) - sc-390417 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dyrk1B (H-6): sc-390417. Western blot analysis of Dyrk1B expression in non-transfected: sc-117752 (A) and human Dyrk1B transfected: sc-158463 (B) whole cell lysates.

Dyrk1B (C-17) - sc-79466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dyrk1B (C-17): sc-79466. Western blot analysis of Dyrk1B expression in non-transfected: sc-117752 (A) and human Dyrk1B transfected: sc-171878 (B) 293T whole cell lysates.

Dyrk1B (N-19) - sc-79467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dyrk1B (N-19): sc-79467. Western blot analysis of Dyrk1B expression in non-transfected: sc-117752 (A) and human Dyrk1B transfected: sc-171878 (B) 293T whole cell lysates.

Dyrk1B (H-45) - sc-98507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Dyrk1B (H-45): sc-98507. Western blot analysis of Dyrk1B expression in non-transfected: sc-117752 (A) and human Dyrk1B transfected: sc-158463 (B) 293T whole cell lysates.

Dyrk1B (Q-20) - sc-79468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dyrk1B (Q-20): sc-79468. Western blot analysis of Dyrk1B expression in non-transfected: sc-117752 (A) and human Dyrk1B transfected: sc-171878 (B) 293T whole cell lysates.

Dyrk1B (S-22) - sc-130742 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Dyrk1B antibody - ab113968 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Dyrk1B antibody (ab113968) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-Dyrk1B antibody - ab130297 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Dyrk1B antibody (ab130297) at 1/100 dilution + 293 cell line lysate at 35 µgdeveloped using the ECL technique

Anti-Dyrk1B antibody - ab135976 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Dyrk1B antibody (ab135976) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-Dyrk1B antibody - ab69879 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Dyrk1B antibody (ab69879) at 1/500 dilutionLane 1 : Dyrk1B transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-Dyrk1B antibody [EPR5617] - ab124960 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5617
All lanes : Anti-Dyrk1B antibody [EPR5617] (ab124960) at 1/1000 dilutionLane 1 : HT 1080 cell lysatesLane 2 : Neuro 2a cell lysatesLane 3 : SW480 cell lysatesLane 4 : HeLa cell lysatesLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-DYRK1B Antibody (aa68-85) - LS-C148933 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (Thr356) - LS-C192055 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa567-597, AP) - LS-C234803 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa567-597, APC) - LS-C234804 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa567-597, FITC) - LS-C234806 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa567-597, Biotin) - LS-C234805 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa376-403, APC) - LS-C234809 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa376-403, AP) - LS-C234808 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa567-597, PE) - LS-C234807 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa376-403, Biotin) - LS-C234810 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK1B Antibody (aa376-403, FITC) - LS-C234811 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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