DYRK1B

Gene Symbol DYRK1B
Entrez Gene 9149
Alt Symbol AOMS3, MIRK
Species Human
Gene Type protein-coding
Description dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Other Description dual specificity tyrosine-phosphorylation-regulated kinase 1B|minibrain-related kinase|mirk protein kinase
Swissprots O75789 Q9Y463 O75258 O75788
Accessions AAC28914 EAW56916 EAW56917 EAW56918 EAW56919 EAW56920 EAW56921 EAW56922 EAW56923 EAW56924 Q9Y463 AF205861 AAF15893 AK074971 BAG52042 AK302127 BAG63504 BC009688 BC018751 AAH18751 BC025291 AAH25291 BI964831 BQ446787 DQ892536 ABM83462 DQ895747 ABM86673 HY024135 Y17999 CAA76989 XM_005259395 XP_005259452 XM_005259398 XP_005259455 XM_011527469 XP_011525771 XM_011527470 XP_011525772 XM_011548813 XP_011547115 XM_011548814 XP_011547116 XM_011548815 XP_011547117 XM_011548816 XP_011547118 NM_004714 NP_004705 NM_006483 NP_006474 NM_006484 NP_006475
Function Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC). {ECO:0000269|PubMed:10910078, ECO:0000269|PubMed:11980910, ECO:0000269|PubMed:14500717, ECO:0000269|PubMed:24827035}.
Subcellular Location Nucleus.
Tissue Specificity Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. {ECO:0000269|PubMed:10910078}.

Dyrk1B CRISPR/Cas9 KO Plasmid (h) - sc-403880 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B HDR Plasmid (h) - sc-403880-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B Double Nickase Plasmid (h) - sc-403880-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B Double Nickase Plasmid (h2) - sc-403880-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B CRISPR Activation Plasmid (h) - sc-403880-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B CRISPR Activation Plasmid (h2) - sc-403880-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B Lentiviral Activation Particles (h) - sc-403880-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B Lentiviral Activation Particles (h2) - sc-403880-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dyrk1B siRNA (h) - sc-77210 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dyrk1B shRNA Plasmid (h) - sc-77210-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dyrk1B shRNA (h) Lentiviral Particles - sc-77210-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dyrk1B RNAi - H00009149-R07 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU076811 from Sigma-Aldrich

Category siRNA

MISSION® siRNA - SIHK0642 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0644 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0641 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0643 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2238 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2238 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03619 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03619

DYRK1B siRNA (Human) - CRH6055 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Dyrk1B RNAi - H00009149-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Dyrk1B RNAi - H00009149-R09 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DYRK1B - MBS8239523 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DYRK1B (NM_004714.1) - SHH282277 from Creative biogene

Category siRNA
Species Reactivities Human
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