DYRK1B

Gene Symbol	DYRK1B
Entrez Gene	9149
Alt Symbol	AOMS3, MIRK
Species	Human
Gene Type	protein-coding
Description	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Other Description	dual specificity tyrosine-phosphorylation-regulated kinase 1B|minibrain-related kinase|mirk protein kinase
Swissprots	O75789 Q9Y463 O75258 O75788
Accessions	AAC28914 EAW56916 EAW56917 EAW56918 EAW56919 EAW56920 EAW56921 EAW56922 EAW56923 EAW56924 Q9Y463 AF205861 AAF15893 AK074971 BAG52042 AK302127 BAG63504 BC009688 BC018751 AAH18751 BC025291 AAH25291 BI964831 BQ446787 DQ892536 ABM83462 DQ895747 ABM86673 HY024135 Y17999 CAA76989 XM_005259395 XP_005259452 XM_005259398 XP_005259455 XM_011527469 XP_011525771 XM_011527470 XP_011525772 XM_011548813 XP_011547115 XM_011548814 XP_011547116 XM_011548815 XP_011547117 XM_011548816 XP_011547118 NM_004714 NP_004705 NM_006483 NP_006474 NM_006484 NP_006475
Function	Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC). {ECO:0000269|PubMed:10910078, ECO:0000269|PubMed:11980910, ECO:0000269|PubMed:14500717, ECO:0000269|PubMed:24827035}.
Subcellular Location	Nucleus.
Tissue Specificity	Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. {ECO:0000269|PubMed:10910078}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dyrk1B full length protein - ab160359 from Abcam Category Protein Source Wheat germ Species Human

Human Dyrk1B protein fragment - ab160360 from Abcam Category Protein Source Wheat germ Species Human

DYRK1B Antibody Blocking Peptide - LS-E3438 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DYRK1B Antibody Blocking Peptide - LS-E4424 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DYRK1B Antibody Blocking Peptide - LS-E9034 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Dyrk1B Protein - H00009149-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Dyrk1B Protein - H00009149-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Dyrk1B Peptide - P2545 from Novus Biologicals Category Peptide Species Human

DYRK1B-Antibody-Center-Blocking-Peptide - BP16734c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DYRK1B-Antibody-C-term-Blocking-peptide - BP7538b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DYRK1B - H00009149-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DYRK1B - H00009149-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DYRK1B - H00009149-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DYRK1B - H00009149-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DYRK1B - P5540 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

DYRK1B fusion protein - Ag2883 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DYRK1B, GST-tagged - DYRK1B-12237H from Creative Biomart Category Protein Source E.coli Species Human

Dyrk1B (T356) Peptide - BS2677P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

DYRK1B Blocking Peptide - abx061251 from Abbexa Category Peptide Species Human, Mouse, Bovine

Dyrk1B Recombinant Protein Antigen - NBP1-82643PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DYRK1B Peptide, Human - M34GP04653H from Creative Peptides Category Peptide Source Synthetic. Species Human

DYRK1B Blocking Peptide - CBP5164 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Bovine

Dyrk1B Recombinant Protein Antigen - NBP2-55096PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DYRK1B peptide - orb319310 from Biorbyt Category Peptide

Recombinant Human DYRK1B Protein, GST-tagged - DYRK1B-22H from Creative Biomart Category Protein Source Insect cells Species Human

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