DYRK1B

Gene Symbol	DYRK1B
Entrez Gene	9149
Alt Symbol	AOMS3, MIRK
Species	Human
Gene Type	protein-coding
Description	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Other Description	dual specificity tyrosine-phosphorylation-regulated kinase 1B|minibrain-related kinase|mirk protein kinase
Swissprots	O75789 Q9Y463 O75258 O75788
Accessions	AAC28914 EAW56916 EAW56917 EAW56918 EAW56919 EAW56920 EAW56921 EAW56922 EAW56923 EAW56924 Q9Y463 AF205861 AAF15893 AK074971 BAG52042 AK302127 BAG63504 BC009688 BC018751 AAH18751 BC025291 AAH25291 BI964831 BQ446787 DQ892536 ABM83462 DQ895747 ABM86673 HY024135 Y17999 CAA76989 XM_005259395 XP_005259452 XM_005259398 XP_005259455 XM_011527469 XP_011525771 XM_011527470 XP_011525772 XM_011548813 XP_011547115 XM_011548814 XP_011547116 XM_011548815 XP_011547117 XM_011548816 XP_011547118 NM_004714 NP_004705 NM_006483 NP_006474 NM_006484 NP_006475
Function	Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC). {ECO:0000269|PubMed:10910078, ECO:0000269|PubMed:11980910, ECO:0000269|PubMed:14500717, ECO:0000269|PubMed:24827035}.
Subcellular Location	Nucleus.
Tissue Specificity	Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. {ECO:0000269|PubMed:10910078}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DYRK1B 293T Cell Transient Overexpression Lysate(Denatured) - H00009149-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DYRK1B 293 Cell Lysate - 401354 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Dyrk1B Overexpression Lysate (Denatured) - H00009149-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Dyrk1B Overexpression Lysate (Native) - NBL1-10075 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Dyrk1B (h2): 293T Lysate - sc-171878 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Dyrk1B (h3): 293T Lysate - sc-158463 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

DYRK1B Over-expression Lysate Product - GWB-158CFB from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Dyrk1B Overexpression Lysate (Denatured) - H00009149-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human DYRK1B Knockdown Stable Cell Line - CSC-DC004653 from Creative biogene Category Cell Line Species Human

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