RDH16

Gene Symbol RDH16
Entrez Gene 8608
Alt Symbol RODH-4, SDR9C8
Species Human
Gene Type protein-coding
Description retinol dehydrogenase 16 (all-trans)
Other Description microsomal NAD(+)-dependent retinol dehydrogenase 4|microsomal NAD+-dependent retinol dehydrogenase 4|retinol dehydrogenase 16|retinol dehydrogenase 16 (all-trans and 13-cis)|short chain dehydrogenase/reductase family 9C member 8|short chain dehydrogenase/reductase family 9C, member 8|sterol/retinol dehydrogenase
Swissprots O75452 Q9UNV2
Accessions EAW96968 O75452 AB209332 BAD92569 AF057034 AAC39922 AF086735 AAC72923 AK311025 AW449664 BC160081 AAI60081 DQ499468 ABF51671 XM_005269205 XP_005269262 XM_011538923 XP_011537225 XM_011538924 XP_011537226 NM_003708 NP_003699
Function Oxidoreductase with a preference for NAD. Oxidizes all- trans-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction. {ECO:0000269|PubMed:10329026, ECO:0000269|PubMed:12534290, ECO:0000269|PubMed:9677409}.
Subcellular Location Microsome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Tissue Specificity Highly expressed in adult liver (at protein level). Detected in endometrium, liver and foreskin. Detected in the spineous layers of adult skin, and at lower levels in basal and granular skin layers. Detected in fetal liver and lung. {ECO:0000269|PubMed:10329026, ECO:0000269|PubMed:11967490, ECO:0000269|PubMed:9677409}.
Top Pathways Retinol metabolism

RDH16 (S-14) - sc-169127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Retinol dehydrogenase 16 antibody - ab89653 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Retinol dehydrogenase 16 antibody - ab84344 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Retinol dehydrogenase 16 antibody (ab84344) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Retinol dehydrogenase 16 antibody - ab169667 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Retinol dehydrogenase 16 antibody (ab169667) at 1 µg/mlLane 1 : Retinol dehydrogenase 16-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-RDH16 Antibody (aa3-31) - LS-C162525 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RDH16 Antibody (N-term immunohistochemistry of formalin-fixed and paraffin-embedded human skin carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RDH16 Antibody (Internal) - LS-C145067 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa3-31, AP) - LS-C239892 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa3-31, FITC) - LS-C239894 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa3-31, APC) - LS-C239893 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa3-31, Biotin) - LS-C239895 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa3-31, PE) - LS-C239897 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa3-31, Azide-free, HRP) - LS-C248642 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa10-39) - LS-C324599 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDH16 Antibody (aa215-264) - LS-C116200 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RDH16 antibody LS-C116200 Western blot of COLO205 cell lysate.

Anti-RDH16 Antibody (N-Terminus) - LS-C101945 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RDH16 antibody LS-C101945 Western blot of 721_B cell lysate.

RDH16 Antibody - NBP1-87117 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RDH16 Antibody [NBP1-87117] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.

RDH16 Antibody - NBP1-58060 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RDH16 Antibody [NBP1-58060] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

RDH16 Antibody - NBP1-58059 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RDH16 Antibody [NBP1-58059] - COLO205 cells lysate, concentration 0.2-1 ug/ml.

RDH16 Antibody - NBP1-30011 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

RDH16 Antibody - H00008608-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-RDH16 antibody produced in rabbit - HPA038518 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RDH16: <B>Cat. No. HPA038518</B>: Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Anti-RDH16 antibody produced in rabbit - SAB2101973 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RDH16: <B>Cat. No.SAB2101973</B>: RDH16 in 721_B cell lysate with RDH16 antibody at 1.0 μg/mL.

Anti-RDH16 antibody produced in rabbit - SAB2105453 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RDH16: <B>Cat. No. SAB2105453</B>: RDH16 in COLO205 cell lysates with RDH16 antibody at 1.0 μg/mL.

RDH16 antibody - N-terminal region (ARP42141_P050) - ARP42141_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RDH16 antibody - middle region (ARP42142_P050) - ARP42142_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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