NR0B2

Gene Symbol	NR0B2
Entrez Gene	8431
Alt Symbol	SHP, SHP1
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 0, group B, member 2
Other Description	nuclear receptor SHP|nuclear receptor subfamily 0 group B member 2|orphan nuclear receptor SHP|small heterodimer partner
Swissprots	Q5QP36 F1D8P5 Q15466
Accessions	AAC41998 BAB68530 EAX07781 Q15466 AA872285 AI457167 AK310048 BC030207 AAH30207 DA930064 HQ692833 ADZ17344 XM_011542297 XP_011540599 NM_021969 NP_068804
Function	Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box- containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1. {ECO:0000269|PubMed:14752053}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:14752053}. Cytoplasm {ECO:0000269|PubMed:14752053}. Note=Colocalizes with NEUROD1 in the nucleus.
Tissue Specificity	Liver. Low levels of expression were detected in heart and pancreas. {ECO:0000269|PubMed:8650544}.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-NR0B2-cDNA-Clone - DC06064 from Abgent, a WuXi AppTec company Prices $346.95 Sizes 10 µg Species Human Accession BC030207

NR0B2 cDNA (ANA10224) - ANA10224 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC030207

NR0B2 - MBS1268340 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC030207

Human NR0B2 Gene ORF cDNA clone in cloning vector - HG14043-G from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14043-NH from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14043-NF from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14043-NM from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14043-CF from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14043-CH from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14043-CM from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14043-NY from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14043-ANG from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14043-ACR from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14043-ANR from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid - HG14043-UT from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14043-CY from Sino Biological Species Human

Human NR0B2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14043-ACG from Sino Biological Species Human

Human NR0B2 ORF Clone (BC030207) - CDCS415397 from Creative biogene Species Human Accession Q15466

Human NR0B2 ORF clone (BC030207) - CDCB159442 from Creative biogene Species Human

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