NR0B2

Gene Symbol	NR0B2
Entrez Gene	8431
Alt Symbol	SHP, SHP1
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 0, group B, member 2
Other Description	nuclear receptor SHP|nuclear receptor subfamily 0 group B member 2|orphan nuclear receptor SHP|small heterodimer partner
Swissprots	Q5QP36 F1D8P5 Q15466
Accessions	AAC41998 BAB68530 EAX07781 Q15466 AA872285 AI457167 AK310048 BC030207 AAH30207 DA930064 HQ692833 ADZ17344 XM_011542297 XP_011540599 NM_021969 NP_068804
Function	Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box- containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1. {ECO:0000269|PubMed:14752053}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:14752053}. Cytoplasm {ECO:0000269|PubMed:14752053}. Note=Colocalizes with NEUROD1 in the nucleus.
Tissue Specificity	Liver. Low levels of expression were detected in heart and pancreas. {ECO:0000269|PubMed:8650544}.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR0B2 full length protein - ab132488 from Abcam Category Protein Source Wheat germ Species Human

Human NR0B2 protein fragment - ab127096 from Abcam Category Protein Source E. coli Species Human

NR0B2 Antibody Blocking Peptide - LS-E721 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR0B2 Antibody Blocking Peptide - LS-E29066 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NR0B2 Antibody Blocking Peptide - LS-E12840 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR0B2 Antibody Blocking Peptide - LS-E12839 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR0B2 Antibody Blocking Peptide - LS-E16664 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR0B2 Antibody Blocking Peptide - LS-E16665 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SHP/NR0B2/Nuclear Receptor SHP Protein - H00008431-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NR0B2-Antibody-Center-Blocking-peptide - BP11075c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NR0B2 Protein Lysate (APL10224) - APL10224 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

NR0B2 Blocking Peptide - 33R-8889 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR0B2 Blocking Peptide - 33R-1113 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR0B2 - H00008431-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NR0B2 - H00008431-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NR0B2 fusion protein - ag3878 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NR0B2 fusion protein - ag4411 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Small Heterodimer Partner (SHP) - RPC266Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Small Heterodimer Partner (SHP) - RPC266Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Nuclear receptor subfamily 0 group B member 2(NR0B2) - CSB-YP624025HU CSB-EP624025HU CSB-BP624025HU CSB-MP624025HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NR0B2 (full length, N-term HIS tag) - TP760144 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

Recombinant Small Heterodimer Partner (SHP) - RPC266Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

NR0B2 Peptide, Human - M34GP10584H from Creative Peptides Category Peptide Source Synthetic. Species Human

NR0B2 Protein Lysate - orb333194 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

Recombinant Small Heterodimer Partner (SHP) - RPU52127 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

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