CXCL6

Gene Symbol CXCL6
Entrez Gene 6372
Alt Symbol CKA-3, GCP-2, GCP2, SCYB6
Species Human
Gene Type protein-coding
Description chemokine (C-X-C motif) ligand 6
Other Description C-X-C motif chemokine 6|Small inducible cytokine subfamily B (Cys-X-Cys), member b|chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)|chemokine alpha 3|granulocyte chemotactic protein 2|small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)|small-inducible cytokine B6
Swissprots B2R4X3 P80162 Q4W5D4
Accessions AAC51338 AAY40939 EAX05690 P80162 AK311981 BAG34920 BC013744 AAH13744 BP204144 DQ891500 ABM82426 DQ894692 ABM85618 U81234 AAD00506 Y08770 CAA70023 NM_002993 NP_002984
Function Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram- negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Rheumatoid arthritis, Pertussis

GCP-2 (H-86) - sc-366202 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

GCP-2 (T-16) - sc-5813 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GCP-2 (T-16): sc-5813. Western blot analysis of human recombinant GCP-2.

Anti-CXCL5 + CXCL6 antibody [EP13083] - ab198505 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP13083
Anti-CXCL5 + CXCL6 antibody [EP13083] (ab198505) at 1/5000 dilution + A549 (Human lung carcinoma) cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-GCP2 antibody - ab9923 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GCP2 antibody - ab87300 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GCP2 antibody (ab87300) at 1 µg/ml + Transfected 293T cell lysate at 10 µgSecondaryanti-Rabbit IgG HRP at 1/50000 dilution

Anti-GCP2 antibody (Biotin) - ab83138 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-GCP2 antibody [EPR8840] - ab151731 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8840
Anti-GCP2 antibody [EPR8840] (ab151731) at 1/1000 dilution + Tagged recombinant Human GCP2 protein at 10 µgSecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-GCP2 antibody [MM0217-10L25] - ab89326 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MM0217-10L25

Anti-CXCL6 Antibody - LS-C104344 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western Blot (reducing) of CXCL6 antibody LS-C104344

Anti-CXCL6 Antibody (clone 11n76, APC) - LS-C184759 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 11n76

Anti-CXCL6 Antibody (clone 2G3) - LS-C198169 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2G3

Anti-CXCL6 Antibody (Biotin) - LS-C104349 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXCL6 Antibody - LS-C310045 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXCL6 Antibody (C-Terminus) - LS-C101337 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CXCL6 antibody LS-C101337 Western blot of Transfected 293T cell lysate.

CXCL6/GCP-2 Antibody - NBP1-33078 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GCP2 Antibody [NBP1-33078] - Sample (30 ug of whole cell lysate) A: A431 B: Hela 7. 5% SDS PAGE; antibody diluted at 1:1000.

CXCL6/GCP-2 Antibody - AF333 from Novus Biologicals

Prices $99.00, $369.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Recombinant Human CXCL6/GCP‑2 (Catalog # 333-GC) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CXCL6/GCP‑2 (80 ng/mL) is neutral­ized (green line) by increasing concentrations of Goat Anti-Human CXCL6/GCP‑2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF333). The ND50 is typically 0.8‑4.0 µg/mL.

CXCL6/GCP-2 Antibody - H00006372-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CXCL6/GCP-2 Antibody [H00006372-D01P] - Analysis of CXCL6 expression in transfected 293T cell line by CXCL6 polyclonal antibody.Lane 1: CXCL6 transfected lysate(11.90 KDa).Lane 2: Non-transfected lysate.

CXCL6/GCP-2 Antibody (MM0217-10L25) - NBP2-12232 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0217-10L25

CXCL6/GCP-2 Antibody - H00006372-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

CXCL6/GCP-2 Antibody [Biotin] - BAF333 from Novus Biologicals

Prices $420.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

CXCL6/GCP-2 Antibody (60910) [Allophycocyanin] - IC333A from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 60910

CXCL6/GCP-2 Antibody (2G12) - H00006372-M10 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G12
Sandwich ELISA: CXCL6/GCP-2 Antibody (2G12) [H00006372-M10] - Detection limit for recombinant GST tagged CXCL6 is 1 ng/ml as a capture antibody.

CXCL6/GCP-2 Antibody (2G3) - H00006372-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G3

Anti-CXCL6 antibody produced in rabbit - SAB2103319 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CXCL6, antibody produced in rabbit: <B>Cat. No. SAB2103319</B>: Immunoblotting analysis of CXCL6 in transfected 293T cell lysate with CXCL6 anitbody at 1 μg/mL.

Monoclonal Anti-CXCL6 antibody produced in mouse - SAB1402912 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G12
<B>ELISA</B><BR/>Monoclonal Anti-CXCL6: <B>Cat. No. SAB1402912</B>: Detection limit for recombinant GST tagged CXCL6 is 1 ng/mL.
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