CASQ2

Gene Symbol	CASQ2
Entrez Gene	845
Alt Symbol	PDIB2
Species	Human
Gene Type	protein-coding
Description	calsequestrin 2 (cardiac muscle)
Other Description	calsequestrin 2, fast-twitch, cardiac muscle|calsequestrin, cardiac muscle isoform|calsequestrin-2
Swissprots	Q8TBW8 Q5T1D2 O14958 B4DIB0 B2R7M6
Accessions	CCQ43132 EAW56635 EAW56636 O14958 AK129831 AK129891 AK225959 AK293595 BAG57061 AK295502 BAG58422 AK313041 BAG35873 BC022288 AAH22288 BM679349 D55655 BAA23494 DC423064 DQ893219 ABM84145 DQ896548 ABM87547 NM_001232 NP_001223
Function	Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. {ECO:0000269|PubMed:16908766, ECO:0000269|PubMed:17881003, ECO:0000269|PubMed:18399795, ECO:0000269|PubMed:21416293}.
Subcellular Location	Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:O09161}. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells. {ECO:0000250|UniProtKB:O09161}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CASQ2 gene - orb91611 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-CASQ2-cDNA-Clone - DC05224 from Abgent, a WuXi AppTec company Prices $538.65 Sizes 10 µg Species Human Accession BC022288

CASQ2 - MBS1272543 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC022288

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone in cloning vector - HG11115-M from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11115-M-F from Sino Biological Species Human

Human CASQ2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11115-M-N from Sino Biological Species Human Accession NM_001232.3

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid - HG11115-UT from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11115-ACG from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11115-NY from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, N-His tag - HG11115-NH from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11115-NF from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11115-NM from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-His tag - HG11115-CH from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11115-CF from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11115-CM from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11115-ACR from Sino Biological Species Human

Human Calsequestrin 2/CASQ2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11115-CY from Sino Biological Species Human

CASQ2 - CL01319H01 from Elabscience Species Human Accession NM_001232.3

Human CASQ2 ORF Clone (BC022288) - CDCS409731 from Creative biogene Species Human Accession O14958

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