LAMP2

Gene Symbol	LAMP2
Entrez Gene	3920
Alt Symbol	CD107b, LAMP-2, LAMPB, LGP110
Species	Human
Gene Type	protein-coding
Description	lysosomal-associated membrane protein 2
Other Description	CD107 antigen-like family member B|lysosome-associated membrane glycoprotein 2
Swissprots	Q99534 Q96J30 Q6Q3G8 A8K4X5 Q16641 P13473 D3DTF0 Q9UD93
Accessions	AAB41647 AAB67313 AAB67314 EAX11881 EAX11882 EAX11883 EAX11884 P13473 AK291090 BAF83779 AK293931 BAG57310 AK295038 BAH11955 AK304405 BAG65239 AY561849 AAS67876 BC002965 AAH02965 BC040653 BP386088 DA405328 DQ892095 ABM83021 DQ895288 ABM86214 J04183 AAA60383 S79873 AAB35426 U36336 AAA91149 X77196 CAA54416 NM_001122606 NP_001116078 NM_002294 NP_002285 NM_013995 NP_054701
Function	Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. {ECO:0000269|PubMed:8407947}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE- ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Endosome membrane {ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Lysosome membrane {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Tissue Specificity	Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.
Top Pathways	Lysosome, Phagosome, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LAMP2-Over-expression-Lysate - LY11496a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CD107b / LAMP2 Lysate(Denatured) - H00003920-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

LAMP2 overexpression lysate - LY419414 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LAMP-2/CD107b Overexpression Lysate (Denatured) - H00003920-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

LAMP-2/CD107b Overexpression Lysate (Native) - NBP2-08128 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

LAMP-2/CD107b Overexpression Lysate (Native) - NBP2-07403 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Cynomolgus LAMP2 HEK293 Cell Lysate (WB positive control) - 90208-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human LAMP2 / CD107b HEK293 Cell Lysate (WB positive control) - 13555-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human LAMP2 Human Cells Transfected Lysate (positive control) (denatured) - orb232935 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

LAMP2-knockout Cell lysate - LC810126 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human LAMP2 Knockdown Stable Cell Line - CSC-DC008532 from Creative biogene Category Cell Line Species Human

Human LAMP2 Knockout Cell Line-HeLa - CSC-RT0594 from Creative biogene Category Cell Line Species Human

LAMP2 KO Cell Lysate-HeLa - CLKO-0099 from Creative biogene Category Cell Lysate

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