LAMP2

Gene Symbol	LAMP2
Entrez Gene	3920
Alt Symbol	CD107b, LAMP-2, LAMPB, LGP110
Species	Human
Gene Type	protein-coding
Description	lysosomal-associated membrane protein 2
Other Description	CD107 antigen-like family member B|lysosome-associated membrane glycoprotein 2
Swissprots	Q99534 Q96J30 Q6Q3G8 A8K4X5 Q16641 P13473 D3DTF0 Q9UD93
Accessions	AAB41647 AAB67313 AAB67314 EAX11881 EAX11882 EAX11883 EAX11884 P13473 AK291090 BAF83779 AK293931 BAG57310 AK295038 BAH11955 AK304405 BAG65239 AY561849 AAS67876 BC002965 AAH02965 BC040653 BP386088 DA405328 DQ892095 ABM83021 DQ895288 ABM86214 J04183 AAA60383 S79873 AAB35426 U36336 AAA91149 X77196 CAA54416 NM_001122606 NP_001116078 NM_002294 NP_002285 NM_013995 NP_054701
Function	Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. {ECO:0000269|PubMed:8407947}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE- ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Endosome membrane {ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Lysosome membrane {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Tissue Specificity	Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.
Top Pathways	Lysosome, Phagosome, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LAMP2 peptide - ab39802 from Abcam Category Peptide Species Human

Human LAMP2 peptide - ab98943 from Abcam Category Peptide

Human LAMP2 protein fragment - ab114167 from Abcam Category Protein Source Wheat germ Species Human

Human LAMP2a peptide - ab23322 from Abcam Category Peptide

Human LAMP2b peptide - ab23321 from Abcam Category Peptide

Human LAMP2b protein fragment - ab151915 from Abcam Category Protein Source HEK 293 cells Species Human

LAMP2 peptide - ab4937 from Abcam Category Peptide

LAMP2 / CD107b Antibody Blocking Peptide - LS-E5715 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LAMP2 / CD107b Antibody Blocking Peptide - LS-E5716 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LAMP2 / CD107b Antibody Blocking Peptide - LS-E30183 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LAMP-2/CD107b Partial Recombinant Protein - H00003920-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

LAMP-2/CD107b Blocking Peptide - NBP1-76653PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

LAMP-2/CD107b Recombinant Protein - H00003920-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

LAMP2-Antibody-Center-Blocking-Peptide - BP1824c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LAMP2-Antibody-C-term-Blocking-Peptide - BP1824b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human LAMP2/CD107b, CF - 6228-LM-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu29-Phe375, with a C-terminal 10-His tag

LAMP2 Protein (OPPA00181) - OPPA00181 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Sf9 insect cells.

Cynomolgus LAMP2 protein (His Tag) - orb139266 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

Human LAMP2 (His Tag) protein - orb232312 from Biorbyt Category Protein Prices $400.00, $816.00 Sizes 50 μg, 200 μg Species Human

Human LAMP2 protein - orb168713 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source Sf9 insect cells.

Human CD107b protein - orb49525 from Biorbyt Category Protein Prices $272.00, $366.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

LAMP2 Blocking Peptide - 33R-10989 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Human LAMP2 Protein - abx067860 from Abbexa Category Protein Source E.coli Species Human

Human LAMP2 Protein - abx067862 from Abbexa Category Protein Source E.coli Species Human

CD107b / LAMP2 - H00003920-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

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