LAMP2

Gene Symbol	LAMP2
Entrez Gene	3920
Alt Symbol	CD107b, LAMP-2, LAMPB, LGP110
Species	Human
Gene Type	protein-coding
Description	lysosomal-associated membrane protein 2
Other Description	CD107 antigen-like family member B|lysosome-associated membrane glycoprotein 2
Swissprots	Q99534 Q96J30 Q6Q3G8 A8K4X5 Q16641 P13473 D3DTF0 Q9UD93
Accessions	AAB41647 AAB67313 AAB67314 EAX11881 EAX11882 EAX11883 EAX11884 P13473 AK291090 BAF83779 AK293931 BAG57310 AK295038 BAH11955 AK304405 BAG65239 AY561849 AAS67876 BC002965 AAH02965 BC040653 BP386088 DA405328 DQ892095 ABM83021 DQ895288 ABM86214 J04183 AAA60383 S79873 AAB35426 U36336 AAA91149 X77196 CAA54416 NM_001122606 NP_001116078 NM_002294 NP_002285 NM_013995 NP_054701
Function	Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. {ECO:0000269|PubMed:8407947}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE- ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Endosome membrane {ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Lysosome membrane {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Tissue Specificity	Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.
Top Pathways	Lysosome, Phagosome, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LAMP2 Gene cDNA Clone - orb144034 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-LAMP2-cDNA-Clone - DC01194 from Abgent, a WuXi AppTec company Prices $553.50 Sizes 10 µg Species Human Accession BC002965

Human LAMP-2A/CD107b (NP_002285) VersaClone cDNA - RDC0977 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human LAMP-2B/CD107b (NP_054701) VersaClone cDNA - RDC1003 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

LAMP2 - MBS1275848 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002965

Human LAMP2 cDNA clone(NM_001122606.1) - CDFH010192 from Creative Biomart Species Human Accession NM_001122606.1

Human LAMP2 ORF Clone(NM_001122606.1) - CDCR348222 from Creative Biomart Species Human Accession NM_001122606.1

Human LAMP2 ORF Clone(NM_001122606.1) - CDCR348223 from Creative Biomart Species Human Accession NM_001122606.1

Human LAMP2 ORF Clone(NM_001122606.1) - CDCL168435 from Creative Biomart Species Human Accession NM_001122606.1

Human LAMP2 ORF Clone(NM_013995.2) - CDCL168436 from Creative Biomart Species Human Accession NM_013995.2

Human LAMP2 Gene cDNA clone plasmid - HG13555-G from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid - HG13555-UT from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13555-ACR from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, N-HA tag - HG13555-NY from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13555-NF from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13555-NM from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13555-CF from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13555-CM from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13555-ACG from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, N-His tag - HG13555-NH from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, C-HA tag - HG13555-CY from Sino Biological Species Human

Human LAMP2/CD107b Gene ORF cDNA clone expression plasmid, C-His tag - HG13555-CH from Sino Biological Species Human

Human LAMP2 ORF clone (NM_001122606.1) - CDCL126133 from Creative biogene Species Human

Human LAMP2 ORF Clone (BC002965) - CDCS407696 from Creative biogene Species Human Accession P13473

Human LAMP2 ORF clone (BC002965) - CDCB159888 from Creative biogene Species Human

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