Gene Symbol | GPD1L |
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Entrez Gene | 23171 |
Alt Symbol | GPD1-L |
Species | Human |
Gene Type | protein-coding |
Description | glycerol-3-phosphate dehydrogenase 1-like |
Other Description | glycerol-3-phosphate dehydrogenase 1-like protein |
Swissprots | Q14702 Q8N335 A8K9U3 Q9BRM5 |
Accessions | EAW64421 EAW64422 Q8N335 AI080105 AK074221 AK125404 BAG54194 AK292808 BAF85497 BC006168 AAH06168 BC028726 AAH28726 BX283865 D42047 BAA07648 DA318838 XM_005264983 XP_005265040 XM_006713068 XP_006713131 NM_015141 NP_055956 |
Function | Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L. {ECO:0000269|PubMed:19666841, ECO:0000269|PubMed:19745168}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17967977}. Note=Localized to the region of the plasma membrane. |
Tissue Specificity | Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs. {ECO:0000269|PubMed:17967977}. |
Top Pathways | Glycerophospholipid metabolism |
GPD1L (E-17) - sc-102569 from Santa Cruz Biotechnology
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GPD1L (I-12) - sc-102570 from Santa Cruz Biotechnology
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Anti-GPD1L antibody - ab107509 from Abcam
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Anti-GPD1L antibody - ab68799 from Abcam
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Anti-GPD1L antibody - ab83406 from Abcam
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Anti-GPD1L Antibody (C-Terminus) - LS-C102593 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73) - LS-C166604 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73, AP) - LS-C257915 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73, APC) - LS-C257916 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73, Biotin) - LS-C257917 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73, FITC) - LS-C257918 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73, Azide-free, HRP) - LS-C257919 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa44-73, PE) - LS-C257920 from LifeSpan Bioscience
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Anti-GPD1L Antibody - LS-C307738 from LifeSpan Bioscience
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Anti-GPD1L Antibody - LS-C311183 from LifeSpan Bioscience
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Anti-GPD1L Antibody - LS-C311186 from LifeSpan Bioscience
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Anti-GPD1L Antibody (aa47-77) - LS-C321719 from LifeSpan Bioscience
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GPD1L Antibody - NBP1-32279 from Novus Biologicals
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GPD1L Antibody - NBP1-81548 from Novus Biologicals
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Glycerol 3 Phosphate Dehydrogenase Antibody - NBP1-87411 from Novus Biologicals
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GPD1L Antibody - H00023171-B01P from Novus Biologicals
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GPD1L Antibody - H00023171-D01P from Novus Biologicals
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GPD1L Antibody - H00023171-D01 from Novus Biologicals
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Anti-GPD1L antibody produced in rabbit - SAB2100954 from Sigma-Aldrich
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Anti-GPD1L antibody produced in mouse - SAB1400442 from Sigma-Aldrich
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