IL1RL2

Gene Symbol	IL1RL2
Entrez Gene	8808
Alt Symbol	IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2
Species	Human
Gene Type	protein-coding
Description	interleukin 1 receptor-like 2
Other Description	IL-1 receptor-related protein 2|IL-36 receptor|interleukin-1 receptor-like 2|interleukin-1 receptor-related protein 2
Swissprots	A4FU63 Q53TU8 Q45H74 Q587I8 Q13525 Q9HB29
Accessions	AAX81989 AAY15046 AAZ38712 EAX01798 Q9HB29 AF284434 AAG21368 AK315334 BAG37734 BC107064 AAI07065 U49065 AAB53237 XM_005264035 XP_005264092 XM_005264036 XP_005264093 XM_006712820 XP_006712883 XM_006712822 XP_006712885 XM_011512090 XP_011510392 XM_011512091 XP_011510393 XM_011512092 XP_011510394 XM_011512093 XP_011510395 XM_011512094 XP_011510396 XM_011512095 XP_011510397 XM_011512096 XP_011510398 XM_011512097 XP_011510399 XM_011512098 XP_011510400 XR_923053 NM_003854 NP_003845
Function	Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL- 23/IL-17/IL-22 pathway. {ECO:0000250|UniProtKB:Q9ERS7, ECO:0000269|PubMed:11466363}.
Subcellular Location	Membrane; Single-pass type I membrane protein {ECO:0000269|PubMed:24829417}.
Tissue Specificity	Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte- derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level. {ECO:0000269|PubMed:16646978, ECO:0000269|PubMed:24829417}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-IL1RL2-cDNA-Clone - DC09455 from Abgent, a WuXi AppTec company Prices $616.95 Sizes 10 µg Species Human Accession BC107064

Human IL-1 Rrp2/IL-1 R6 (NP_003845) VersaClone cDNA - RDC1136 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

IL1RL2 - MBS1268970 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC107064

Human IL1RL2 cDNA clone(NM_003854.2) - CDFH009176 from Creative Biomart Species Human Accession NM_003854.2

Human IL1RL2 ORF Clone(NM_003854.2) - CDCR286626 from Creative Biomart Species Human Accession NM_003854.2

Human IL1RL2 ORF Clone(NM_003854.2) - CDCR286627 from Creative Biomart Species Human Accession NM_003854.2

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone in cloning vector - HG14398-G from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14398-CY from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14398-NF from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14398-CF from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14398-NM from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14398-CM from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14398-NH from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14398-NY from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14398-ACG from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14398-CH from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14398-ACR from Sino Biological Species Human

Human IL1RL2/IL1RRP2 Gene ORF cDNA clone expression plasmid - HG14398-UT from Sino Biological Species Human

Human IL1RL2 ORF clone (NM_003854.2) - CDCL120407 from Creative biogene Species Human

Human IL1RL2 ORF Clone (BC107064) - CDCS411508 from Creative biogene Species Human Accession Q9HB29

Human IL1RL2 Gene cDNA Clone - orb143767 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human IL1RL2 cDNA Clone(NM_003854.2) - CDFH009176 from Creative biogene Species Human

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