IL1RL2

Gene Symbol	IL1RL2
Entrez Gene	8808
Alt Symbol	IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2
Species	Human
Gene Type	protein-coding
Description	interleukin 1 receptor-like 2
Other Description	IL-1 receptor-related protein 2|IL-36 receptor|interleukin-1 receptor-like 2|interleukin-1 receptor-related protein 2
Swissprots	A4FU63 Q53TU8 Q45H74 Q587I8 Q13525 Q9HB29
Accessions	AAX81989 AAY15046 AAZ38712 EAX01798 Q9HB29 AF284434 AAG21368 AK315334 BAG37734 BC107064 AAI07065 U49065 AAB53237 XM_005264035 XP_005264092 XM_005264036 XP_005264093 XM_006712820 XP_006712883 XM_006712822 XP_006712885 XM_011512090 XP_011510392 XM_011512091 XP_011510393 XM_011512092 XP_011510394 XM_011512093 XP_011510395 XM_011512094 XP_011510396 XM_011512095 XP_011510397 XM_011512096 XP_011510398 XM_011512097 XP_011510399 XM_011512098 XP_011510400 XR_923053 NM_003854 NP_003845
Function	Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL- 23/IL-17/IL-22 pathway. {ECO:0000250|UniProtKB:Q9ERS7, ECO:0000269|PubMed:11466363}.
Subcellular Location	Membrane; Single-pass type I membrane protein {ECO:0000269|PubMed:24829417}.
Tissue Specificity	Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte- derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level. {ECO:0000269|PubMed:16646978, ECO:0000269|PubMed:24829417}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL1RL2 protein fragment - ab160204 from Abcam Category Protein Source Wheat germ Species Human

IL1RL2 Antibody Blocking Peptide - LS-E2392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IL1RL2 Protein - H00008808-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IL1RL2-Antibody-Center-Blocking-peptide - BP13370c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human IL-1 Rrp2/IL-1 R6 Fc Chimera, CF - 872-RP-100 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Human IL1RL2 (Fc Tag) protein - orb232330 from Biorbyt Category Protein Prices $323.00, $638.00 Sizes 20 μg, 100 μg Species Human

IL1RL2 Blocking Peptide - 33R-3869 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

IL1RL2 / IL1RRP2 - H00008808-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IL1RL2 / IL1RRP2 - H00008808-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

IL-1RL2 Peptide - 7501P from ProSci Category Peptide Species Human

IL1RL2 fusion protein - ag16600 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IL1RL2 fusion protein - ag17984 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

IL1RL2 fusion protein - ag21974 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Interleukin 1 Receptor-Like 2 - IL1RL2-1639H from Creative Biomart Category Protein Source Sf 21 Insect Cells.

Human IL1RL2 / IL-1Rrp2 Protein (Fc Tag) - 14398-H02H-20 from Sino Biological Category Protein Prices $98.00, $248.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

Recombinant Human Interleukin-1 receptor-like 2(IL1RL2) - CSB-YP888016HU CSB-EP888016HU CSB-BP888016HU CSB-MP888016HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human IL-1 Rrp2/IL-1 R6 Fc Chimera Protein, CF - 872-RP from R&D Systems Category Protein Prices $429.00 Sizes 100 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Human IL-1 R6 (Asp20 - Tyr337) Accession # Q9HB29 DIEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Human

Human IL1RL2 / IL-1Rrp2 Protein (His Tag) - 14398-H08H-20 from Sino Biological Category Protein Source Human Cells Species Human

Human IL-36R protein (C-Fc) - orb311826 from Biorbyt Category Protein Prices $281.00, $553.00, $1,598.00, $2,406.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Recombinant Human IL1RL2 protein, His-tagged - IL1RL2-336H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human IL1RL2 protein, Fc-tagged - IL1RL2-337H from Creative Biomart Category Protein Source HEK293 Species Human

IL1RL2 Recombinant Protein Antigen - NBP1-81594PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IL1RL2 Peptide, Human - M34GP07568H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human IL-1RL2 protein - orb5369 from Biorbyt Category Protein Prices $306.00, $680.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human IL1RL2 / IL-1Rrp2 Protein (Fc Tag) - 14398-H02H from ABclonal Category Protein Prices $98.00, $248.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

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