Gene Symbol | TIFA |
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Entrez Gene | 92610 |
Alt Symbol | T2BP, T6BP, TIFAA |
Species | Human |
Gene Type | protein-coding |
Description | TRAF-interacting protein with forkhead-associated domain |
Other Description | TRAF-interacting protein with FHA domain-containing protein A|TRAF-interacting protein with a forkhead-associated domain|TRAF2 binding protein|TRAF2-binding protein|TRAF6 binding protein|putative MAPK-activating protein PM14|putative NF-kappa-B-activating protein 20 |
Swissprots | Q96CG3 |
Accessions | AAY40963 EAX06273 Q96CG3 AB062110 BAB86902 AB097011 BAC77364 AB097038 BAC77391 AK292900 BAF85589 BC008294 AAH08294 BC014259 AAH14259 BM680110 BM718895 CA772080 DQ893681 ABM84607 DQ896122 ABM87121 XM_011532413 XP_011530715 NM_052864 NP_443096 |
Function | Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. {ECO:0000269|PubMed:12566447, ECO:0000269|PubMed:15492226}. |
T2BP (G-14) - sc-163417 from Santa Cruz Biotechnology
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T2BP (K-14) - sc-163418 from Santa Cruz Biotechnology
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T2BP (N-14) - sc-163419 from Santa Cruz Biotechnology
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Anti-TIFA antibody - ab103011 from Abcam
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Anti-T6BP / TIFA Antibody - LS-C47465 from LifeSpan Bioscience
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Anti-T6BP / TIFA Antibody (aa150-162) - LS-C191351 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79, AP) - LS-C241793 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79, APC) - LS-C241795 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79, FITC) - LS-C241796 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79, Biotin) - LS-C241797 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79, PE) - LS-C241798 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79, Azide-free, HRP) - LS-C247066 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa58-88) - LS-C325725 from LifeSpan Bioscience
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Anti-TIFA Antibody (aa52-79) - LS-C161876 from LifeSpan Bioscience
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Anti-TIFA (121-135) antibody produced in rabbit - SAB1102688 from Sigma-Aldrich
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Anti-TIFA antibody produced in rabbit - HPA045889 from Sigma-Aldrich
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TIFA-Antibody-N-term - AP9587a from Abgent, a WuXi AppTec company
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TIFA Antibody - N-terminal region (OAAB06182) - OAAB06182 from Aviva Systems Biology
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TIFA / T2BP (N-term) antibody - AP54249PU-N from Acris Antibodies
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Rabbit Anti-Human TIFA (N-term) - 102-18321 from RayBiotech
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TIFA antibody (N-term) - STJ52028 from St John's Laboratory Ltd
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TIFA antibody - 11333-1-AP from Proteintech Group
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TAX1BP1 Polyclonal Antibody - ESAP10814 from Elabscience
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TAX1BP1 Polyclonal Antibody - ESAP14713 from Elabscience
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Anti-TIFA monoclonal antibody - DCABH-17114 from Creative Diagnostics
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