Gene Symbol | TIFA |
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Entrez Gene | 92610 |
Alt Symbol | T2BP, T6BP, TIFAA |
Species | Human |
Gene Type | protein-coding |
Description | TRAF-interacting protein with forkhead-associated domain |
Other Description | TRAF-interacting protein with FHA domain-containing protein A|TRAF-interacting protein with a forkhead-associated domain|TRAF2 binding protein|TRAF2-binding protein|TRAF6 binding protein|putative MAPK-activating protein PM14|putative NF-kappa-B-activating protein 20 |
Swissprots | Q96CG3 |
Accessions | AAY40963 EAX06273 Q96CG3 AB062110 BAB86902 AB097011 BAC77364 AB097038 BAC77391 AK292900 BAF85589 BC008294 AAH08294 BC014259 AAH14259 BM680110 BM718895 CA772080 DQ893681 ABM84607 DQ896122 ABM87121 XM_011532413 XP_011530715 NM_052864 NP_443096 |
Function | Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. {ECO:0000269|PubMed:12566447, ECO:0000269|PubMed:15492226}. |
Human-TIFA-cDNA-Clone - DC03798 from Abgent, a WuXi AppTec company
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TIFA - MBS1278866 from MyBioSource
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Human TIFA cDNA clone(NM_052864.2) - CDFG006981 from Creative Biomart
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Human TIFA ORF Clone(NM_052864.2) - CDCR314252 from Creative Biomart
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Human TIFA ORF Clone(NM_052864.2) - CDCR314254 from Creative Biomart
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Human TIFA ORF Clone(NM_052864.2) - CDCR314257 from Creative Biomart
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human TIFA ORF clone - CDCH088334 from Creative Biomart
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human TIFA ORF clone - CDCH088335 from Creative Biomart
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Human TIFA ORF Clone(NM_052864.2) - CDCL178481 from Creative Biomart
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Human TIFA ORF Clone(NM_052864.2) - CDCR314252 from Creative biogene
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Human TIFA ORF Clone (BC014259) - CDCS416548 from Creative biogene
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Human TIFA cDNA Clone(NM_052864.2) - CDFG006981 from Creative biogene
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