SPN

Gene Symbol	SPN
Entrez Gene	6693
Alt Symbol	CD43, GALGP, GPL115, LSN
Species	Human
Gene Type	protein-coding
Description	sialophorin
Other Description	galactoglycoprotein|leukocyte sialoglycoprotein|leukosialin|sialophorin (gpL115, leukosialin, CD43)
Swissprots	P16150 A8K9B1
Accessions	AAA51949 CAA36294 EAW80015 EAW80016 P16150 AK292626 BAF85315 AK313750 BAG36490 BC012350 AAH12350 BC035510 DA951208 DB108930 DQ892262 ABM83188 DQ895464 ABM86390 J04536 AAB59540 X60502 NM_001030288 NP_001025459 NM_003123 NP_003114
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
Top Pathways	Cell adhesion molecules (CAMs), Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Leukosialin, SPN, Human, ELISA Kit - E1778h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

SPN (Human) Matched Antibody Pair - H00006693-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

sialophorin, ELISA Kit - MBS9328541 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sialophorin (SPN), ELISA Kit - MBS9311072 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human SPN / CD43 ELISA Kit (Custom ELISA) - LS-F18507 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Rat SPN / CD43 ELISA Kit (Custom ELISA) - LS-F18509 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Mouse SPN / CD43 ELISA Kit (Custom ELISA) - LS-F18508 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Human Leukosialin ELISA Kit - abx251245 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human Leukosialin ELISA Kit - EKE54021 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.053 ng/mL Range 0.156-10 ng/mL

SPN - EKH3852 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Human SPN ELISA Kit - E022640 from Biobool Category ELISA Kit Sensitivity <0.094ng/ml

SPN ELISA Kit (Human) (OKEH04707) - OKEH04707 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity < 0.07 ng/mL Range 0.156 - 10 ng/mL

anti-CD43 antibody [DF-T1] (PE) - ARG21361 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [DF-T1] - ARG21358 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [DF-T1] (FITC) - ARG21359 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [DF-T1] (Biotin) - ARG21360 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [DF-T1] (APC) - ARG21362 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [DF-T1] (RPE/Cy5) - ARG21363 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [W3/13] - ARG23064 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [SP55] - ARG52778 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [84-3C1] - ARG56077 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [MEM-59] - ARG62848 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [MEM-59] (low endotoxin) - ARG65500 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody [W3/13] (FITC) - ARG23063 from Arigo Biolaboratories Category ELISA Kit

anti-CD43 antibody - ARG52776 from Arigo Biolaboratories Category ELISA Kit

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