HMGA1

Gene Symbol HMGA1
Entrez Gene 3159
Alt Symbol HMG-R, HMGA1A, HMGIY
Species Human
Gene Type protein-coding
Description high mobility group AT-hook 1
Other Description HMG-I(Y)|high mobility group protein A1|high mobility group protein HMG-I/HMG-Y|high mobility group protein R|high-mobility group (nonhistone chromosomal) protein isoforms I and Y|nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y
Swissprots Q5T6U9 P10910 Q9UKB0 P17096
Accessions AAB00145 CBX54360 EAX03762 EAX03763 EAX03764 EAX03765 EAX03766 EAX03767 EAX03768 EAX03769 EAX03770 EAX03771 EAX03772 EAX03773 EAX03774 P17096 AF176039 AAD53889 AK096863 AK130027 BAC85280 AK301434 BAG62962 AK308245 BC004924 AAH04924 BC008832 AAH08832 BC008963 BC015789 AAH15789 BC063434 AAH63434 BC067083 AAH67083 BC071863 AAH71863 BC071864 AAH71864 BC078664 BT006774 AAP35420 DA049639 DA574958 DC338100 DC374225 DQ893097 ABM84023 EU176767 ABW03568 KF731633 M23614 AAA88072 M23615 AAA88073 M23616 AAA88074 M23617 AAA88075 M23618 AAA88076 M23619 AAA35998 X14957 CAA33080 X14958 CAA33081 XM_005249061 XP_005249118 XM_011514565 XP_011512867 NM_002131 NP_002122 NM_145899 NP_665906 NM_145901 NP_665908 NM_145902 NP_665909 NM_145903 NP_665910 NM_145905 NP_665912 NM_145904
Function HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Subcellular Location Nucleus. Chromosome.

HMGA1 (D6A4) XP ® Rabbit mAb - 7777 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6A4
Western blot analysis of extracts from various cell lines using HMGA1 (D6A4) XP ® Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

HMGA1 (D4F8) Rabbit mAb - 12094 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4F8
Western blot analysis of extracts from NCCIT and NTERA2 cl.D1 cells using HMGA1 (D4F8) Rabbit mAb.

HMG-I/HMG-Y (FL-95) - sc-8982 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HMG-I/HMG-Y (FL-95): sc-8982. Western blot analysis of HMG-I/HMG-Y expression in mouse spleen tissue extract.

HMG-I/HMG-Y (D-12) - sc-393213 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HMG-I/HMG-Y (D-12): sc-393213. Western blot analysis of HMG-I/HMG-Y expression in JAR (A) and SK-OV-3 (B) whole cell lysates.

HMG-I/HMG-Y (N-19) - sc-1564 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HMG-I/HMG-Y (N-19): sc-1564. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing nuclear staining of glandular cells.

HMG-I/HMG-Y (T-16) - sc-26348 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HMGA1 antibody - ab134759 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HMGA1 antibody (ab134759) at 1/500 dilution + mouse brain tissue extract at 30 µg

Anti-HMGA1 antibody [EPR16649] - ab202070 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16649
All lanes : Anti-HMGA1 antibody [EPR16649] (ab202070) at 1/10000 dilutionLane 1 : NCCIT (Human pluripotent embryonal carcinoma) whole cell lysateLane 2 : BxPC-3 (Human pancreas adenocarcinoma cells) whole cell lysateLane 3 : HepG2 (Human liver hepatocellular carcinoma) whole cell lysateLane 4 : SK-OV-3 (Human ovarian cancer cell line) whole cell lysateLane 5 : Caco-2 (Human colorectal adenocarcinoma cells) whole cell lysateLane 6 : Human testis lysateLane 7 : Human lung lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-HMGA1 antibody [EPR7839] - ab129153 from Abcam

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7839
All lanes : Anti-HMGA1 antibody [EPR7839] (ab129153) at 10000 (purified)Lane 1 : HepG2 cell lysateLane 2 : SK-OV-3 cell lysateLane 3 : Caco-2 cell lysateLane 4 : BxPC-3 cell lysateLysates/proteins at 20 µg per lane.SecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-HMGA1a / HMGA1b antibody - ChIP Grade - ab4078 from Abcam

Prices $398.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluoresence on MCF-7 cells transfected with human HMGA1a-GFP using ab4078.A: Hoechst stainB: PhasecontrastC: TexasRed HMG-I/HMG-Y (ab4078)D: HMGA1a-GFPE: Merge

Anti-HMGIY / HMGA1 Antibody (aa81-93) - LS-C47447 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody (aa1-96) - LS-C129876 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody (N-Terminus) - LS-C135054 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HMGA1 antibody LS-C135054 Western blot of HT1080 cell lysate.

Anti-HMGIY / HMGA1 Antibody (aa45-94) - LS-C199887 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from mouse brain tissue, using HMG-I/HMG-Y antibody.

Anti-HMGIY / HMGA1 Antibody (N-Terminus) - LS-C169520 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody (aa3-107, Biotin) - LS-C298121 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody (clone 2A1) - LS-C197423 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A1
Immunofluorescence of monoclonal antibody to HMGA1 on HeLa cell . [antibody concentration 10 ug/ml]

Anti-HMGIY / HMGA1 Antibody (aa3-107) - LS-C294503 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant HMGIY / HMGA1.

Anti-HMGIY / HMGA1 Antibody (aa3-107, FITC) - LS-C302231 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody - LS-C308270 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody - LS-C341094 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HMGIY / HMGA1 Antibody (N-Terminus) - LS-C345669 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of HMGA1 Antibody with human Jurkat Whole Cell lysate.

Anti-HMGIY / HMGA1 Antibody (Internal, clone EPR7839) - LS-C154446 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7839
IHC of paraffin-embedded human testis tissue using anti-HMGA1 antibody.

Anti-HMGIY / HMGA1 Antibody (aa1-50) IHC-plus™ - LS-B2037 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HMGA1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2037 concentration 10 ug/ml.

Anti-HMGIY / HMGA1 Antibody (aa64-93) - LS-C164930 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of A549 cell stained with HMGA1 Antibody. A549 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HMGA1 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). HMGA1 immunoreactivity is localized to Nucleus significantly.
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