RAET1G

Gene Symbol RAET1G
Entrez Gene 353091
Alt Symbol ULBP5
Species Human
Gene Type protein-coding
Description retinoic acid early transcript 1G
Other Description UL-16 binding protein 5|retinoic acid early transcript 1G protein
Swissprots Q6H3X2 Q6H3X3
Accessions AFP99104 AFP99105 AFP99106 EAW47779 Q6H3X3 AK310157 AY172579 AAO22238 AY172580 AAO22239 BC096719 AAH96719 BC098152 AAH98152 HY165961 XM_011535800 XP_011534102 NM_001001788 NP_001001788 NR_130110
Function Acts as a ligand for the KLRK1 receptor and mediates NK cell cytotoxicity via the receptor. {ECO:0000269|PubMed:15240696}.
Subcellular Location Isoform 1: Cell membrane {ECO:0000269|PubMed:19223974}; Single-pass type I membrane protein {ECO:0000269|PubMed:19223974}. Cell membrane {ECO:0000269|PubMed:19223974}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:19223974}. Endoplasmic reticulum {ECO:0000269|PubMed:19223974}. Note=Mainly found inside the cell, with a minority of the protein reaching the cell surface.
Tissue Specificity Isoform 1 is highly expressed in colon and in a number of tumor cell lines and highly restricted in normal tissues. Both isoforms are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers. {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974}.
Top Pathways Natural killer cell mediated cytotoxicity

Human RAET1G cDNA clone(NM_001001788.2) - CDFH015840 from Creative Biomart

Species Human
Accession NM_001001788.2

Human RAET1G ORF Clone(NM_001001788.2) - CDCR338474 from Creative Biomart

Species Human
Accession NM_001001788.2

Human RAET1G ORF Clone(NM_001001788.2) - CDCR338475 from Creative Biomart

Species Human
Accession NM_001001788.2

human RAET1G ORF clone (NM_001001788.2) - CDCH071262 from Creative biogene

Species Human

Human RAET1G cDNA Clone(NM_001001788.2) - CDFH015840 from Creative biogene

Species Human
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