Gene Symbol | RAET1G |
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Entrez Gene | 353091 |
Alt Symbol | ULBP5 |
Species | Human |
Gene Type | protein-coding |
Description | retinoic acid early transcript 1G |
Other Description | UL-16 binding protein 5|retinoic acid early transcript 1G protein |
Swissprots | Q6H3X2 Q6H3X3 |
Accessions | AFP99104 AFP99105 AFP99106 EAW47779 Q6H3X3 AK310157 AY172579 AAO22238 AY172580 AAO22239 BC096719 AAH96719 BC098152 AAH98152 HY165961 XM_011535800 XP_011534102 NM_001001788 NP_001001788 NR_130110 |
Function | Acts as a ligand for the KLRK1 receptor and mediates NK cell cytotoxicity via the receptor. {ECO:0000269|PubMed:15240696}. |
Subcellular Location | Isoform 1: Cell membrane {ECO:0000269|PubMed:19223974}; Single-pass type I membrane protein {ECO:0000269|PubMed:19223974}. Cell membrane {ECO:0000269|PubMed:19223974}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:19223974}. Endoplasmic reticulum {ECO:0000269|PubMed:19223974}. Note=Mainly found inside the cell, with a minority of the protein reaching the cell surface. |
Tissue Specificity | Isoform 1 is highly expressed in colon and in a number of tumor cell lines and highly restricted in normal tissues. Both isoforms are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers. {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974}. |
Top Pathways | Natural killer cell mediated cytotoxicity |
Human RAET1G full length protein - ab167931 from Abcam
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Human RAET1G full length protein - ab166345 from Abcam
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Human RAET1G protein fragment - ab166346 from Abcam
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ULBP5 / RAET1G Antibody Blocking Peptide - LS-E23868 from LifeSpan Bioscience
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Recombinant Human ULBP-5/RAET1G Protein - H00353091-P01 from Novus Biologicals
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Recombinant Human ULBP-5/RAET1G Protein - H00353091-Q01 from Novus Biologicals
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Recombinant Human ULBP-5, CF - 7149-UL-050 from R&D Systems
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Human RAET1G protein - orb191262 from Biorbyt
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RAET1G - H00353091-P01-10 from Acris Antibodies
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RAET1G - H00353091-P01-25 from Acris Antibodies
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RAET1G - H00353091-Q01-10 from Acris Antibodies
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RAET1G - H00353091-Q01-25 from Acris Antibodies
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Recombinant Human RAET1G, His-tagged - RAET1G-629H from Creative Biomart
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Recombinant Human Retinoic acid early transcript 1G protein(RAET1G) - CSB-YP750234HU CSB-EP750234HU CSB-BP750234HU CSB-MP750234HU from Cusabio
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Recombinant Human ULBP-5 Protein, CF - 7149-UL from R&D Systems
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Retinoic Acid Early Transcript 1G Protein (Recombinant) - abx262670 from Abbexa
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RAET1G Peptide, Human - M34GP12926H from Creative Peptides
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Retinoic Acid Early Transcript 1G, Human Recombinant - 228-21716-1 from RayBiotech
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Retinoic Acid Early Transcript 1G, Recombinant Protein - MBS146578 from MyBioSource
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Retinoic acid early transcript 1G protein (RAET1G), Recombinant Protein - MBS1292564 from MyBioSource
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Recombinant Human ULBP-5 Protein, CF - 7149-UL from Novus Biologicals
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