GP6

Gene Symbol GP6
Entrez Gene 51206
Alt Symbol BDPLT11, GPIV, GPVI
Species Human
Gene Type protein-coding
Description glycoprotein VI (platelet)
Other Description glycoprotein 6|platelet collagen receptor|platelet glycoprotein VI
Swissprots Q9UIF2 Q9HCN6 Q9HCN7
Accessions AAN86273 BAB12248 EAW72324 EAW72325 EAW72326 Q9HCN6 AB035073 BAA89353 AB043819 BAB12245 AB043820 BAB12246 AB043821 BAB12247 BC069485 BC104832 AAI04833 BC111963 AAI11964 BQ216894 NM_001083899 NP_001077368 NM_001256017 NP_001242946 NM_016363 NP_057447
Function Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. {ECO:0000269|PubMed:10961879}.
Subcellular Location Isoform 1: Cell membrane; Single-pass membrane protein.
Tissue Specificity Megakaryocytes and platelets. {ECO:0000269|PubMed:10961879}.
Top Pathways ECM-receptor interaction

GP6 293 Cell Lysate - 402231 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

GPVI Overexpression Lysate (Native) - NBL1-11211 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Glycoprotein VI Overexpression Lysate (Adult Normal) [NBL1-11211] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Glycoprotein VI.

GP6 Over-expression Lysate Product - GWB-A4D9D9 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human GP6 Knockdown Stable Cell Line - CSC-DC006468 from Creative biogene

Category Cell Line
Species Human
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