GP6

Gene Symbol	GP6
Entrez Gene	51206
Alt Symbol	BDPLT11, GPIV, GPVI
Species	Human
Gene Type	protein-coding
Description	glycoprotein VI (platelet)
Other Description	glycoprotein 6|platelet collagen receptor|platelet glycoprotein VI
Swissprots	Q9UIF2 Q9HCN6 Q9HCN7
Accessions	AAN86273 BAB12248 EAW72324 EAW72325 EAW72326 Q9HCN6 AB035073 BAA89353 AB043819 BAB12245 AB043820 BAB12246 AB043821 BAB12247 BC069485 BC104832 AAI04833 BC111963 AAI11964 BQ216894 NM_001083899 NP_001077368 NM_001256017 NP_001242946 NM_016363 NP_057447
Function	Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. {ECO:0000269|PubMed:10961879}.
Subcellular Location	Isoform 1: Cell membrane; Single-pass membrane protein.
Tissue Specificity	Megakaryocytes and platelets. {ECO:0000269|PubMed:10961879}.
Top Pathways	ECM-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GP6 / GPVI Antibody Blocking Peptide - LS-E7933 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GP6 / GPVI Antibody Blocking Peptide - LS-E17133 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GP6 / GPVI Antibody Blocking Peptide - LS-E30558 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GP6 / GPVI Antibody Blocking Peptide - LS-E30559 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPVI Blocking Peptide - NBP1-76941PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

GPVI Blocking Peptide - NBP1-76359PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

GP6-Antibody-C-term-Blocking-peptide - BP5691b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human GPVI, CF - 3627-GP-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gln21-Lys267, with a C-terminal 6-His tag

Human GP6 Protein - abx066887 from Abbexa Category Protein Source E.coli Species Human

Platelet glycoprotein VI Control Peptide - AP30378CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Platelet glycoprotein VI Control Peptide - AP30379CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Glycoprotein VI, Platelet (GP6), Human - 20-8130 from ARP American Research Products Category Protein Prices $505.00 Sizes 50 µg Source E.coli Species Human

GPVI Peptide - 4769P from ProSci Category Peptide Species Human

GPVI Peptide - 4771P from ProSci Category Peptide Species Human

GP6 fusion protein - ag13068 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Glycoprotein 6 (platelet), His-tagged - GP6-5623H from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived.

Recombinant Glycoprotein VI, Platelet (GP6) - RPB904Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Glycoprotein VI, Platelet (GP6) - RPB904Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Platelet glycoprotein VI(GP6) - CSB-YP872550HU CSB-EP872550HU CSB-BP872550HU CSB-MP872550HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human GPVI Protein, CF - 3627-GP from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Gln21-Lys267, with a C-terminal 6-His tag Species Human

GPVI (201-339) - sc-4529 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

Platelet glycoprotein VI (GP6), Recombinant Protein - MBS1403339 from MyBioSource Category Protein Prices $995.00, $995.00, $1,225.00, $1,225.00, $1,525.00, $1,525.00, $1,990.00, $1,990.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

GPV1, Peptide - MBS843889 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

GPVI Recombinant Protein Antigen - NBP2-39074PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GP6 Peptide, Human - M34GP06468H from Creative Peptides Category Peptide Source Synthetic. Species Human

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