CERK

Gene Symbol	CERK
Entrez Gene	64781
Alt Symbol	LK4, dA59H18.2, dA59H18.3, hCERK
Species	Human
Gene Type	protein-coding
Description	ceramide kinase
Other Description	acylsphingosine kinase|lipid kinase 4|lipid kinase LK4
Swissprots	Q9UGE5 Q8TCT0 Q6NX59 A8K611 Q9BYB3 A0JNT4
Accessions	EAW73438 EAW73439 EAW73440 EAW73441 EAW73442 Q8TCT0 AB051433 BAB33316 AB079066 BAC01154 AJ457828 CAD29884 AK025083 AK026892 BAB15585 AK291476 BAF84165 AL137600 AL832794 BC004278 AAH04278 BC008382 BC067255 AAH67255 BC108712 AAI08713 BC126940 AAI26941 BQ710170 BU187541 CR456404 CAG30290 CR457365 CAG33646 CU012949 CAK54380 CU013237 CAK54679 XM_011530315 XP_011528617 NM_182661 NM_022766 NP_073603
Function	Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. {ECO:0000269|PubMed:19168031}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19168031}. Membrane {ECO:0000269|PubMed:19168031}; Peripheral membrane protein {ECO:0000269|PubMed:19168031}.
Tissue Specificity	High level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CERK-cDNA-Clone - DC01439 from Abgent, a WuXi AppTec company Prices $271.35 Sizes 10 µg Species Human Accession BC004278

CERK - MBS1276692 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004278

CERK - MBS1272218 from MyBioSource Species Human Accession BC126940

Human CERK Gene ORF cDNA clone in cloning vector - HG12264-G from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid - HG12264-UT from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12264-ACR from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG12264-ANR from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, C-His tag - HG12264-CH from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12264-NF from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12264-ACG from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG12264-ANG from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12264-NM from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12264-CF from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, C-HA tag - HG12264-CY from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12264-CM from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, N-HA tag - HG12264-NY from Sino Biological Species Human

Human CERK Gene ORF cDNA clone expression plasmid, N-His tag - HG12264-NH from Sino Biological Species Human

Human CERK ORF Clone(NM_022766.5) - CDCR308113 from Creative biogene Species Human

Human CERK ORF Clone (BC004278) - CDCS415546 from Creative biogene Species Human Accession Q8TCT0

Human CERK ORF Clone (BC126940) - CDCS415547 from Creative biogene Species Human Accession Q8TCT0

Human CERK ORF clone (BC004278) - CDCB160166 from Creative biogene Species Human

Human Acylsphingosine kinase Gene - orb142475 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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