CERK

Gene Symbol	CERK
Entrez Gene	64781
Alt Symbol	LK4, dA59H18.2, dA59H18.3, hCERK
Species	Human
Gene Type	protein-coding
Description	ceramide kinase
Other Description	acylsphingosine kinase|lipid kinase 4|lipid kinase LK4
Swissprots	Q9UGE5 Q8TCT0 Q6NX59 A8K611 Q9BYB3 A0JNT4
Accessions	EAW73438 EAW73439 EAW73440 EAW73441 EAW73442 Q8TCT0 AB051433 BAB33316 AB079066 BAC01154 AJ457828 CAD29884 AK025083 AK026892 BAB15585 AK291476 BAF84165 AL137600 AL832794 BC004278 AAH04278 BC008382 BC067255 AAH67255 BC108712 AAI08713 BC126940 AAI26941 BQ710170 BU187541 CR456404 CAG30290 CR457365 CAG33646 CU012949 CAK54380 CU013237 CAK54679 XM_011530315 XP_011528617 NM_182661 NM_022766 NP_073603
Function	Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. {ECO:0000269|PubMed:19168031}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19168031}. Membrane {ECO:0000269|PubMed:19168031}; Peripheral membrane protein {ECO:0000269|PubMed:19168031}.
Tissue Specificity	High level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CERK full length protein - ab196089 from Abcam Category Protein Prices $858.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human CERK full length protein - ab153492 from Abcam Category Protein Source Wheat germ Species Human

Ceramide Kinase / CERK Antibody Blocking Peptide - LS-E28732 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Ceramide Kinase / CERK Antibody Blocking Peptide - LS-E28976 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Ceramide Kinase / CERK Antibody Blocking Peptide - LS-E8679 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Ceramide Kinase / CERK Antibody Blocking Peptide - LS-E23386 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Ceramide Kinase Blocking Peptide - NB100-2911PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human Ceramide Kinase Protein - H00064781-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Ceramide Kinase Peptide - P2216 from Novus Biologicals Category Peptide Species Human

CERK-Antibody-C-term-Blocking-Peptide - BP7088b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Ceramide Kinase - H00064781-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Ceramide Kinase - H00064781-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CERK fusion protein - ag0746 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Ceramide Kinase (FLAG Tag), Active Human Recombinant Protein - GWB-PSB0F8 from Genway Biotech Category Protein Prices $584.00 Sizes 10 µg Species Human

Ceramide Kinase Active Human Recombinant Protein - GWB-4B5836 from Genway Biotech Category Protein Prices $531.00 Sizes 20 µg Species Human

Recombinant Human CERK, Flag-tagged - CERK-508H from Creative Biomart Category Protein Source Insect cells Species Human

Recombinant Human CERK, GST-tagged - CERK-11123H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CERK, Flag-tagged - CERK-510H from Creative Biomart Category Protein Source Sf9 cells Species Human

Recombinant Ceramide Kinase (CERK) - RPJ459Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Ceramide Kinase (CERK) - RPJ459Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Ceramide kinase(CERK) - CSB-YP005256HU CSB-EP005256HU CSB-BP005256HU CSB-MP005256HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Ceramide kinase (CERK), Recombinant Protein - MBS1479599 from MyBioSource Category Protein Prices $1,330.00, $1,330.00, $1,550.00, $1,550.00, $2,200.00, $2,200.00, $2,660.00, $2,660.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Ceramide Kinase Protein - NBP1-85321PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CERK-Antibody-N-term-Blocking-Peptide - BP7088a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CERK Peptide, Human - M34GP03012H from Creative Peptides Category Peptide Source Synthetic. Species Human

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