CERK

Gene Symbol	CERK
Entrez Gene	64781
Alt Symbol	LK4, dA59H18.2, dA59H18.3, hCERK
Species	Human
Gene Type	protein-coding
Description	ceramide kinase
Other Description	acylsphingosine kinase|lipid kinase 4|lipid kinase LK4
Swissprots	Q9UGE5 Q8TCT0 Q6NX59 A8K611 Q9BYB3 A0JNT4
Accessions	EAW73438 EAW73439 EAW73440 EAW73441 EAW73442 Q8TCT0 AB051433 BAB33316 AB079066 BAC01154 AJ457828 CAD29884 AK025083 AK026892 BAB15585 AK291476 BAF84165 AL137600 AL832794 BC004278 AAH04278 BC008382 BC067255 AAH67255 BC108712 AAI08713 BC126940 AAI26941 BQ710170 BU187541 CR456404 CAG30290 CR457365 CAG33646 CU012949 CAK54380 CU013237 CAK54679 XM_011530315 XP_011528617 NM_182661 NM_022766 NP_073603
Function	Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. {ECO:0000269|PubMed:19168031}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19168031}. Membrane {ECO:0000269|PubMed:19168031}; Peripheral membrane protein {ECO:0000269|PubMed:19168031}.
Tissue Specificity	High level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Ceramide Kinase CRISPR/Cas9 KO Plasmid (h) - sc-404164 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase HDR Plasmid (h) - sc-404164-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase Double Nickase Plasmid (h) - sc-404164-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase Double Nickase Plasmid (h2) - sc-404164-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase CRISPR Activation Plasmid (h) - sc-404164-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase CRISPR Activation Plasmid (h2) - sc-404164-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase Lentiviral Activation Particles (h) - sc-404164-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase Lentiviral Activation Particles (h2) - sc-404164-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Ceramide Kinase siRNA (h) - sc-72868 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Ceramide Kinase shRNA Plasmid (h) - sc-72868-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Ceramide Kinase shRNA (h) Lentiviral Particles - sc-72868-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Ceramide Kinase RNAi - H00064781-R06 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

Ceramide Kinase RNAi - H00064781-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU020721 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK0396 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0392 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0394 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0397 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0395 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0393 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN5981 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5981 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11707 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr11707

CERK siRNA (Human) - CRJ2086 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CERK - MBS8210361 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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