SMYD2

Gene Symbol	SMYD2
Entrez Gene	56950
Alt Symbol	HSKM-B, KMT3C, ZMYND14
Species	Human
Gene Type	protein-coding
Description	SET and MYND domain containing 2
Other Description	N-lysine methyltransferase SMYD2|SET and MYND domain-containing protein 2|histone methyltransferase SMYD2|lysine N-methyltransferase 3C|zinc finger, MYND domain containing 14
Swissprots	I6L9H7 Q9NRG4 Q96AI4 Q5VSH9 Q4V765 B2R9P9
Accessions	EAW93355 EAW93356 EAW93357 EAW93358 Q9NRG4 AF070592 AF226053 AAF86953 AK091590 AK098683 AK313868 BAG36596 AW474469 BC017080 AAH17080 BC028104 AAH28104 BC039890 BC049367 AAH49367 BC057793 BC068511 BC094747 BC098133 AAH98133 BC098276 AAH98276 BC098305 AAH98305 BC098335 AAH98335 BG723585 XR_426790 NM_020197 NP_064582
Function	Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. {ECO:0000269|PubMed:17108971, ECO:0000269|PubMed:17805299, ECO:0000269|PubMed:18065756, ECO:0000269|PubMed:20870719, ECO:0000269|PubMed:21782458, ECO:0000269|PubMed:21880715}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

N-lysine methyltransferase SMYD2 (SMYD2), Human, ELISA Kit - CSB-EL021863HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

N-lysine methyltransferase SMYD2 (SMYD2), Human, ELISA Kit - E01N0575 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

SMYD2 (Human) IP-WB Antibody Pair - H00056950-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SMYD2 (Human) IP-WB Antibody Pair - H00056950-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SMYD2 (Human) Matched Antibody Pair - H00056950-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

N lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7219130 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7224846 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7214648 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7204956 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7201644 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7204465 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7239571 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7240084 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7200174 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7226049 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

N-lysine methyltransferase SMYD2 (SMYD2), ELISA Kit - MBS7249860 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

SET and MYND domain containing 2, ELISA Kit - MBS909432 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human SMYD2 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

Human N-lysine methyltransferase SMYD2(SMYD2) ELISA kit - CSB-EL021863HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml. Range 25 pg/ml-1600 pg/ml

Human N-lysine methyltransferase SMYD2 (SMYD2) ELISA Kit - EKC34831 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

Human SMYD2 ELISA Kit - E034984 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human SMYD2 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

SMYD2 ELISA Kit (Human) (OKCA00739) - OKCA00739 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity 6.25 pg/mL Range 25 pg/mL-1,600 pg/mL

anti-KMT3C / SMYD2 antibody - ARG53995 from Arigo Biolaboratories Category ELISA Kit

N-lysine methyltransferase SMYD2, ELISA Kit - MBS284638 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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