SIRPG

Gene Symbol	SIRPG
Entrez Gene	55423
Alt Symbol	CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1
Species	Human
Gene Type	protein-coding
Description	signal-regulatory protein gamma
Other Description	CD172 antigen-like family member B|CD172g antigen|SIRP beta 2|SIRP-beta-2|SIRP-gamma|signal-regulatory protein beta 2|signal-regulatory protein beta-2
Swissprots	Q9NQK8 Q5D051 Q5JV25 B1AKP6 Q9P1W8 Q8WWA5 Q5MKL4
Accessions	EAX10615 EAX10616 EAX10617 EAX10618 Q9P1W8 AA446468 AB042624 BAA95692 AK124224 AK292745 BAF85434 AY748247 AAV88530 AY748248 AAV88531 BC020629 AAH20629 BC064532 AAH64532 DA008008 DB046293 HQ448099 ADQ32580 XM_005260749 XP_005260806 XM_011529286 XP_011527588 XM_011529287 XP_011527589 NM_001039508 NP_001034597 NM_018556 NP_061026 NM_080816 NP_543006
Function	Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. {ECO:0000269|PubMed:15383453}.
Subcellular Location	Membrane {ECO:0000269|PubMed:15383453}; Single-pass type I membrane protein {ECO:0000269|PubMed:15383453}.
Tissue Specificity	Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection. {ECO:0000269|PubMed:11185750, ECO:0000269|PubMed:15383453}.
Top Pathways	Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SIRPG 293T Cell Transient Overexpression Lysate(Denatured) - H00055423-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SIRPG overexpression lysate - LY413008 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SIRPG overexpression lysate - LY422063 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SIRPG overexpression lysate - LY425641 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SIRPG 293 Cell Lysate - 406309 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SIRP gamma/CD172g Overexpression Lysate (Denatured) - H00055423-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

SIRP gamma/CD172g Overexpression Lysate (Native) - NBL1-15972 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SIRPG Over-expression Lysate Product - GWB-6A4CA5 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Cynomolgus SIRPG / SIRP gamma / CD172g HEK293 Cell Lysate (WB positive control) - 90226-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Cynomolgus SIRPG / SIRP gamma / CD172g HEK293 Cell Lysate (WB positive control) - 90226-C02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human SIRPG / SIRP gamma / CD172g HEK293 Cell Lysate (WB positive control) - 11828-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human SIRPG Human Cells Transfected Lysate (positive control) (denatured) - orb173679 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Panoply™ Human SIRPG Knockdown Stable Cell Line - CSC-DC014266 from Creative biogene Category Cell Line Species Human

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