SIRPG

Gene Symbol	SIRPG
Entrez Gene	55423
Alt Symbol	CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1
Species	Human
Gene Type	protein-coding
Description	signal-regulatory protein gamma
Other Description	CD172 antigen-like family member B|CD172g antigen|SIRP beta 2|SIRP-beta-2|SIRP-gamma|signal-regulatory protein beta 2|signal-regulatory protein beta-2
Swissprots	Q9NQK8 Q5D051 Q5JV25 B1AKP6 Q9P1W8 Q8WWA5 Q5MKL4
Accessions	EAX10615 EAX10616 EAX10617 EAX10618 Q9P1W8 AA446468 AB042624 BAA95692 AK124224 AK292745 BAF85434 AY748247 AAV88530 AY748248 AAV88531 BC020629 AAH20629 BC064532 AAH64532 DA008008 DB046293 HQ448099 ADQ32580 XM_005260749 XP_005260806 XM_011529286 XP_011527588 XM_011529287 XP_011527589 NM_001039508 NP_001034597 NM_018556 NP_061026 NM_080816 NP_543006
Function	Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. {ECO:0000269|PubMed:15383453}.
Subcellular Location	Membrane {ECO:0000269|PubMed:15383453}; Single-pass type I membrane protein {ECO:0000269|PubMed:15383453}.
Tissue Specificity	Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection. {ECO:0000269|PubMed:11185750, ECO:0000269|PubMed:15383453}.
Top Pathways	Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD172 gamma protein fragment - ab172854 from Abcam Category Protein Prices $133.00 Sizes 10 µg Source HEK 293 cells Species Human

Human CD172 gamma protein fragment - ab180289 from Abcam Category Protein Prices $357.00 Sizes 100 µg Source E. coli Species Human

Human CD172 gamma protein fragment - ab191638 from Abcam Category Protein Prices $515.00 Sizes 100 µg Source HEK 293 cells Species Human

SIRPB2 Antibody Blocking Peptide - LS-E6450 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIRPB2 Antibody Blocking Peptide - LS-E24271 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIRPG Antibody Blocking Peptide - LS-E4338 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIRPG Antibody Blocking Peptide - LS-E22830 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIRPG Antibody Blocking Peptide - LS-E23875 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIRP gamma/CD172g Recombinant Protein - H00055423-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

SIRPG-Antibody-Center-Blocking-Peptide - BP16636c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human SIRP gamma/CD172g Fc Chimera, CF - 4486-SB-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

Cynomolgus SIRPG protein - orb139663 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

Human SIRPG protein - orb163532 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human SIRPG His tag protein - orb84131 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus SIRPG protein (His Tag) - orb139662 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

SIRPG protein (His tag) - 80R-3880 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

CD172g / SIRPG (His-tag) - AR51567PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD172g / SIRPG (His-tag) - AR51567PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CD172g / SIRPG - H00055423-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

SIRPG, 29- 360aa, Human, His tag, E.coli - 01-P2747 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

SIRPG, Human, Recombinant - 19-CG10 from ARP American Research Products Category Protein Prices $119.00 Sizes 10 µg Source HEK293 Species Human

sFRP4 Recombinant Protein - 96-688 from ProSci Category Protein Source HEK293 cells Species Human

SIRPG Recombinant Protein - 96-698 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

SIRPG fusion protein - Ag2430 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SIRPG Protein - BP001787-CG10 from Syd Labs Category Protein Prices $98.00, $300.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source HEK 293-derived. Species Human

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