TEAD1

Gene Symbol	TEAD1
Entrez Gene	7003
Alt Symbol	AA, NTEF-1, REF1, TCF-13, TCF13, TEAD-1, TEF-1
Species	Human
Gene Type	protein-coding
Description	TEA domain family member 1 (SV40 transcriptional enhancer factor)
Other Description	protein GT-IIC|transcription factor 13|transcriptional enhancer factor 1|transcriptional enhancer factor TEF-1
Swissprots	E7EV65 P28347 A4FUP2
Accessions	AAB00791 EAW68520 EAW68521 P28347 AB209858 BAD93095 AI189919 AI199443 AK027342 AK075070 AK075176 AK075236 AK310928 AL035973 AL117450 AL133574 AL833289 BC026959 BC115398 AAI15399 BG720371 BU172369 CA420177 CN420966 DR000961 NM_021961 NP_068780
Function	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif. {ECO:0000269|PubMed:18579750, ECO:000
Subcellular Location	Nucleus.
Tissue Specificity	Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.
Top Pathways	Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TEF1 protein fragment - ab152732 from Abcam Category Protein Source Wheat germ Species Human

TEAD1 Antibody Blocking Peptide - LS-E10898 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TEAD1 Antibody Blocking Peptide - LS-E14299 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TEF1 Recombinant Protein - H00007003-P01 from Novus Biologicals Category Protein Species Human

Human TEAD1 protein - orb246794 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

TEAD1 Blocking Peptide - abx063336 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

TEAD1 fusion protein - Ag24624 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

TEAD1 fusion protein - Ag4082 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human TEAD1, GST-tagged - TEAD1-3174H from Creative Biomart Category Protein Source E.coli Species Human

TEAD1 Blocking Peptide - CBP2142 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

TEF-1 Peptide - BS5961P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

BSA Conjugated Vitamin C (VC) - CPA913Ge11 from Cloud-clone Category Protein Source n/a

OVA Conjugated Vitamin C (VC) - CPA913Ge21 from Cloud-clone Category Protein Source n/a

Recombinant Human Transcriptional enhancer factor TEF-1(TEAD1) - CSB-EP023363HU CSB-BP023363HU CSB-MP023363HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Transcriptional enhancer factor TEF-1(TEAD1) - CSB-YP023363HU from Cusabio Category Protein Source Yeast Species Human

TEAD1-Antibody-C-term-Blocking-Peptide - BP6858b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TEAD1 Peptide, Human - M34GP15769H from Creative Peptides Category Peptide Source Synthetic. Species Human

TEAD1 Recombinant Protein (OPCA02813) - OPCA02813 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant Human Transcriptional enhancer factor TEF-1(TEAD1) - RPC20246 from Biomatik Category Protein Prices $106.00, $242.00, $380.00, $594.00, $945.00, $1,424.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Recombinant Homo sapiens Transcriptional enhancer factor TEF-1 - AP72809 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

TEF1 Recombinant Protein Antigen - NBP2-56300PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TEF1 Recombinant Protein Antigen - NBP2-56713PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Human Transcriptional enhancer factor TEF-1 (TEAD1) - RPC22098 from Biomatik Category Protein Prices $276.00, $505.00, $2,491.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

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