SLC11A1

Gene Symbol	SLC11A1
Entrez Gene	6556
Alt Symbol	LSH, NRAMP, NRAMP1
Species	Human
Gene Type	protein-coding
Description	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
Other Description	NRAMP 1|natural resistance-associated macrophage protein 1|solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1|solute carrier family 11 (sodium/phosphate symporters), member 1|solute carrier family 11 member 1
Swissprots	P49279 C0H5Y3
Accessions	AAA57556 AAA57557 AAG15403 AAG15405 AAQ21581 BAA09782 CAA57541 CAD39201 EAW70611 EAW70612 EAW70613 EAW70614 P49279 AB209650 BAD92887 AK294707 BAG57862 AK298667 BAG60835 AK303398 BAG64454 AK307954 AK310914 AK311405 BC033754 BC037550 BC041787 BC071165 AAH71165 CA307182 D38171 BAA07370 D50402 BAA08907 D50403 BAA08908 DB284801 L32185 AAA57521 XM_005246793 XP_005246850 XM_005246794 XP_005246851 XM_006712709 XP_006712772 XM_006712710 XP_006712773 XM_006712711 XP_006712774 XM_011511684 XP_011509986 XM_011511685 XP_011509987 XR_427107 XR_427108 NM_000578 NP_000569 NM_001032220
Function	Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Macrophages; peripheral blood leukocytes, lung, spleen and liver.
Top Pathways	Lysosome, Mineral absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Natural resistance-associated macrophage protein 1 (SLC11A1), Human, ELISA Kit - E01N0574 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Natural resistance-associated macrophage protein 1, ELISA Kit - MBS283452 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7241255 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7225652 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7241270 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7251292 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7217788 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7214735 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7211966 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7223262 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7247076 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Natural resistance-associated macrophage protein 1 (SLC11A1), ELISA Kit - MBS7251199 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

solute carrier family 11 (proton-coupled divalent metal ion transporters) , member 1, ELISA Kit - MBS939156 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human NRAMP-1 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

Human natural resistance-associated macrophage protein 1(NRAMP-1）ELISA kit - CSB-E17597h from Cusabio Category ELISA Kit Sensitivity 6.25pg/ml Range 25 pg/ml-1600 pg/ml

Human SLC11A1 ELISA Kit - E025881 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

SLC11A1 ELISA Kit (Human) (OKCA02291) - OKCA02291 from Aviva Systems Biology Category ELISA Kit Sensitivity 6.25 pg/mL Range 25 - 1,600 pg/mL

Human SLC11A1 ELISA Kit - orb407577 from Biorbyt Category ELISA Kit Sensitivity 6.25pg/ml Range 25 pg/ml-1600 pg/ml

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