PRKAG3

Gene Symbol PRKAG3
Entrez Gene 53632
Alt Symbol AMPKG3
Species Human
Gene Type protein-coding
Description protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Other Description 5'-AMP-activated protein kinase subunit gamma-3|5'-AMP-activated protein kinase, gamma-3 subunit|AMPK gamma-3 chain|AMPK gamma3|AMPK subunit gamma-3
Swissprots Q4V779 Q9UGI9 Q9NRL1 Q4QQG8
Accessions CCQ43548 EAW70656 EAW70657 Q9UGI9 AA256383 AF214519 AAF73987 AJ249977 CAB65117 AK300078 BAG61882 AK300687 BAG62370 AK309865 BC098102 AAH98102 BC098255 AAH98255 BC098277 AAH98277 BC098306 AAH98306 CD628195 W94830 NM_017431 NP_059127
Function AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating alread
Tissue Specificity Skeletal muscle, with weak expression in heart and pancreas.
Top Pathways Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

AMPKγ3 Antibody - 2550 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from RD cells, using AMPKγ3 Antibody.

AMPKγ3 (H-160) - sc-20166 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AMPKγ3 (H-160) sc-20166. Immunofluorescence staining of normal mouse liver frozen section showing cytoplasmic staining.

AMPKγ3 (A-20) - sc-19145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AMPKγ3 (A-20): sc-19145. Western blot analysis of AMPKγ3 expression in HL-60 whole cell lysate.

AMPKγ3 (C-20) - sc-19146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AMPKγ3 (D-22) - sc-130687 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
AMPKγ3 (D-22): sc-130687. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplasmic localization.

Anti-AMPK gamma 3 antibody - ab38228 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AMPK gamma 3 antibody (ab38228) at 1/100 dilution + mouse brain tissue lysateSecondaryHRP-anti-rabbitdeveloped using the ECL technique

Anti-AMPK gamma 3 antibody - ab203214 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human rectal carcinoma tissue labeling AMPK gamma 3 with ab203214 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-AMPK gamma 3 antibody - ab130711 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AMPK gamma 3 antibody (ab130711) at 1/100 dilution + HL60 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-AMPK gamma 3 antibody - ab128376 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AMPK gamma 3 antibody (ab128376) at 1 µg/ml + Human fetal heart lysate at 10 µg

Anti-PRKAG3 / AMPK Gamma 3 Antibody (C-Terminus) - LS-C203268 from LifeSpan Bioscience

Prices $245.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454, AP) - LS-C216938 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454, APC) - LS-C216939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454, Biotin) - LS-C216941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa32-81) - LS-C151607 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRKAG3 / AMPK Gamma 3 antibody Western Blot of Fetal Heart.

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454, FITC) - LS-C216942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454, Azide-free, HRP) - LS-C216943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454, PE) - LS-C216944 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160, AP) - LS-C216945 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160, Biotin) - LS-C216947 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160, APC) - LS-C216946 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160, FITC) - LS-C216948 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160, PE) - LS-C216950 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160, Azide-free, HRP) - LS-C216949 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa131-160) - LS-C324291 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRKAG3 / AMPK Gamma 3 Antibody (aa425-454) - LS-C330007 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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