NGFRAP1

Gene Symbol NGFRAP1
Entrez Gene 27018
Alt Symbol BEX3, Bex, DXS6984E, HGR74, NADE
Species Human
Gene Type protein-coding
Description nerve growth factor receptor (TNFRSF16) associated protein 1
Other Description brain-expressed X-linked protein 3|ovarian granulosa cell 13.0 kDa protein HGR74|p75NTR-associated cell death executor|protein BEX3
Swissprots B2RD17 D3DXA3 Q00994 Q5JQT4 Q5JQT5
Accessions CBX53811 CBX53812 CBX53813 CCQ43433 EAW54710 EAW54711 EAW54712 Q00994 AF187064 AAF75129 AI929106 AK057859 AK315371 BAG37764 AY833562 AAX40680 BC003190 AAH03190 BC051713 BE395284 BQ068114 CD048295 HQ447887 ADQ32371 M38188 AAA63232 NM_001282674 NP_001269603 NM_014380 NP_055195 NM_206915 NP_996798 NM_206917 NP_996800
Function May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases. {ECO:0000250}.
Subcellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity). {ECO:0000250}.
Tissue Specificity Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver. {ECO:0000269|PubMed:15958283}.
Top Pathways Neurotrophin signaling pathway

Bex3 (P-13) - sc-67454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Bex3 (P-13): sc-67454. Western blot analysis of Bex3 expression in PC-3 whole cell lysate.

Anti-NADE antibody - ab21303 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NADE antibody (ab21303) at 1 µg/mlLane 1 : human brain cell lysate with blocking peptide.Lane 2 : human brain cell lysate with Without blocking peptide.

Anti-NADE antibody - ab57186 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57186 NADE antibody at 1ug/ml.

Anti-NGFRAP1 / NADE / Bex Antibody (Internal) - LS-C16680 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa89-103) - LS-C87210 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42, AP) - LS-C264342 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42, FITC) - LS-C264344 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42, Biotin) - LS-C264343 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42, APC) - LS-C264341 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42, PE) - LS-C264347 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42, Azide-free, HRP) - LS-C264346 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa13-42) - LS-C329892 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 / NADE / Bex Antibody (aa14-42) - LS-C158384 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NGFRAP1 Antibody western blot of A375 cell line lysates (35 ug/lane). The NGFRAP1 antibody detected the NGFRAP1 protein (arrow).

Anti-NGFRAP1 / NADE / Bex Antibody - LS-C346340 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using NGFRAP1 antibody.

Anti-NGFRAP1 / NADE / Bex Antibody IHC-plus™ - LS-B532 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NGFRAP1 / NADE antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B532 concentration 5 ug/ml.

NGFRAP1/BEX3/NADE Antibody (672911) - MAB6858 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 672911
Western blot shows lysates of HT‑29 human colon adenocarcinoma cell line, Balb/3T3 mouse embryonic fibroblast cell line, and C2C12 mouse myoblast cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human NGFRAP1/BEX3 Monoclonal Antibody (Catalog # MAB6858) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for NGFRAP1/BEX3 at approximately 15 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

NGFRAP1/BEX3/NADE Antibody - NBP1-31652 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NGFRAP1/BEX3/NADE Antibody [NBP1-31652] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: H1299 15% SDS PAGE; antibody diluted at 1:1000.

NGFRAP1/BEX3/NADE Antibody - NBP1-77149 from Novus Biologicals

Prices $299.00, $329.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: NGFRAP1/BEX3/NADE Antibody [NBP1-77149] - Human brain cell lysates with NADE antibody at 1 u/mL in the presence (A) or absence (B) of blocking peptide.

NGFRAP1/BEX3/NADE Antibody - NBP1-89987 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NGFRAP1/BEX3/NADE Antibody - H00027018-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: NGFRAP1/BEX3/NADE Antibody [H00027018-B01P] - Analysis of NGFRAP1 expression in transfected 293T cell line by NGFRAP1 polyclonal antibody. Lane 1: NGFRAP1 transfected lysate(11.11 KDa). Lane 2: Non-transfected lysate.

NGFRAP1/BEX3/NADE Antibody (4E5) - H00027018-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E5
Sandwich ELISA: NGFRAP1/BEX3/NADE Antibody (4E5) [H00027018-M01] - Detection limit for recombinant GST tagged NGFRAP1 is approximately 0.3ng/ml as a capture antibody.

NGFRAP1/BEX3/NADE Antibody - NBP1-20952 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NGFRAP1/BEX3/NADE Antibody - H00027018-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

NGFRAP1 Polyclonal Antibody - bs-7671R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NGFRAP1 antibody produced in mouse - SAB1407325 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-NGFRAP1: <B>Cat. No. SAB1407325</B>: Antibody concentration: 10 μg/mL using HeLa cell.
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