NGFRAP1

Gene Symbol	NGFRAP1
Entrez Gene	27018
Alt Symbol	BEX3, Bex, DXS6984E, HGR74, NADE
Species	Human
Gene Type	protein-coding
Description	nerve growth factor receptor (TNFRSF16) associated protein 1
Other Description	brain-expressed X-linked protein 3|ovarian granulosa cell 13.0 kDa protein HGR74|p75NTR-associated cell death executor|protein BEX3
Swissprots	B2RD17 D3DXA3 Q00994 Q5JQT4 Q5JQT5
Accessions	CBX53811 CBX53812 CBX53813 CCQ43433 EAW54710 EAW54711 EAW54712 Q00994 AF187064 AAF75129 AI929106 AK057859 AK315371 BAG37764 AY833562 AAX40680 BC003190 AAH03190 BC051713 BE395284 BQ068114 CD048295 HQ447887 ADQ32371 M38188 AAA63232 NM_001282674 NP_001269603 NM_014380 NP_055195 NM_206915 NP_996798 NM_206917 NP_996800
Function	May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases. {ECO:0000250}.
Subcellular Location	Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity). {ECO:0000250}.
Tissue Specificity	Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver. {ECO:0000269|PubMed:15958283}.
Top Pathways	Neurotrophin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Bex3 CRISPR/Cas9 KO Plasmid (h) - sc-408856 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 HDR Plasmid (h) - sc-408856-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 Double Nickase Plasmid (h) - sc-408856-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 Double Nickase Plasmid (h2) - sc-408856-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 CRISPR Activation Plasmid (h) - sc-408856-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 CRISPR Activation Plasmid (h2) - sc-408856-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 Lentiviral Activation Particles (h) - sc-408856-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 Lentiviral Activation Particles (h2) - sc-408856-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Bex3 siRNA (h) - sc-62017 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Bex3 shRNA Plasmid (h) - sc-62017-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Bex3 shRNA (h) Lentiviral Particles - sc-62017-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NGFRAP1/BEX3/NADE RNAi - H00027018-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

NGFRAP1/BEX3/NADE RNAi - H00027018-R06 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU072811 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15273 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15273 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02553 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02553

NGFRAP1 siRNA (Human) - CRH8923 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

NGFRAP1/BEX3/NADE RNAi - H00027018-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human NGFRAP1 (NM_014380.1) - SHH352140 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NGFRAP1(NM_206917.1) - SHR002316 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NGFRAP1(NM_014380.1) - SHR002370 from Creative biogene Category siRNA Species Reactivities Human

Human NGFRAP1 siRNA - orb269425 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

NGFRAP1 shRNA Plasmid (Human) - CHH8923 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

NGFRAP1 miRNA 3'UTR clone - MiUTR1H-06761 from Creative biogene Species Reactivities Human

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