Gene Symbol | NGFRAP1 |
---|---|
Entrez Gene | 27018 |
Alt Symbol | BEX3, Bex, DXS6984E, HGR74, NADE |
Species | Human |
Gene Type | protein-coding |
Description | nerve growth factor receptor (TNFRSF16) associated protein 1 |
Other Description | brain-expressed X-linked protein 3|ovarian granulosa cell 13.0 kDa protein HGR74|p75NTR-associated cell death executor|protein BEX3 |
Swissprots | B2RD17 D3DXA3 Q00994 Q5JQT4 Q5JQT5 |
Accessions | CBX53811 CBX53812 CBX53813 CCQ43433 EAW54710 EAW54711 EAW54712 Q00994 AF187064 AAF75129 AI929106 AK057859 AK315371 BAG37764 AY833562 AAX40680 BC003190 AAH03190 BC051713 BE395284 BQ068114 CD048295 HQ447887 ADQ32371 M38188 AAA63232 NM_001282674 NP_001269603 NM_014380 NP_055195 NM_206915 NP_996798 NM_206917 NP_996800 |
Function | May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases. {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity). {ECO:0000250}. |
Tissue Specificity | Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver. {ECO:0000269|PubMed:15958283}. |
Top Pathways | Neurotrophin signaling pathway |
Human NAD Synthetase full length protein - ab163006 from Abcam
|
||||||||||
Human NAD Synthetase protein fragment - ab163007 from Abcam
|
||||||||||
Human NADE peptide - ab39793 from Abcam
|
||||||||||
Human NADE protein fragment - ab132232 from Abcam
|
||||||||||
Human NADE protein fragment - ab162056 from Abcam
|
||||||||||
NGFRAP1 / NADE / Bex Antibody Blocking Peptide - LS-E5526 from LifeSpan Bioscience
|
||||||||||
NGFRAP1 / NADE / Bex Antibody Blocking Peptide - LS-E30082 from LifeSpan Bioscience
|
||||||||||
NGFRAP1 / NADE / Bex Antibody Blocking Peptide - LS-E26395 from LifeSpan Bioscience
|
||||||||||
Recombinant Human NGFRAP1/BEX3/NADE Protein - H00027018-P01 from Novus Biologicals
|
||||||||||
Recombinant Human NGFRAP1/BEX3/NADE Protein - H00027018-Q01 from Novus Biologicals
|
||||||||||
NGFRAP1/BEX3/NADE Blocking Peptide - NBP1-77149PEP from Novus Biologicals
|
||||||||||
NGFRAP1-Antibody-N-term-Blocking-Peptide - BP18054a from Abgent, a WuXi AppTec company
|
||||||||||
NADE blocking peptide - GTX88746-PEP from GeneTex
|
||||||||||
Recombinant human protein BEX3 (OPCA00171) - OPCA00171 from Aviva Systems Biology
|
||||||||||
Recombinant human protein BEX3 (OPCA01284) - OPCA01284 from Aviva Systems Biology
|
||||||||||
Human BEX3 protein - orb180359 from Biorbyt
|
||||||||||
Human NGFRAP1 protein - orb244404 from Biorbyt
|
||||||||||
Human NGFRAP1 protein - orb245942 from Biorbyt
|
||||||||||
NADE Peptide - AC21-1231-P from Abcore
|
||||||||||
NADE / BEX3 - H00027018-P01-10 from Acris Antibodies
|
||||||||||
NADE / BEX3 - H00027018-P01-25 from Acris Antibodies
|
||||||||||
NADE / BEX3 - H00027018-Q01-10 from Acris Antibodies
|
||||||||||
NADE / BEX3 - H00027018-Q01-25 from Acris Antibodies
|
||||||||||
NADE / BEX3 Control Peptide - AP30573CP-N from Acris Antibodies
|
||||||||||
NADE Peptide - 3359P from ProSci
|