NGFRAP1

Gene Symbol NGFRAP1
Entrez Gene 27018
Alt Symbol BEX3, Bex, DXS6984E, HGR74, NADE
Species Human
Gene Type protein-coding
Description nerve growth factor receptor (TNFRSF16) associated protein 1
Other Description brain-expressed X-linked protein 3|ovarian granulosa cell 13.0 kDa protein HGR74|p75NTR-associated cell death executor|protein BEX3
Swissprots B2RD17 D3DXA3 Q00994 Q5JQT4 Q5JQT5
Accessions CBX53811 CBX53812 CBX53813 CCQ43433 EAW54710 EAW54711 EAW54712 Q00994 AF187064 AAF75129 AI929106 AK057859 AK315371 BAG37764 AY833562 AAX40680 BC003190 AAH03190 BC051713 BE395284 BQ068114 CD048295 HQ447887 ADQ32371 M38188 AAA63232 NM_001282674 NP_001269603 NM_014380 NP_055195 NM_206915 NP_996798 NM_206917 NP_996800
Function May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases. {ECO:0000250}.
Subcellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity). {ECO:0000250}.
Tissue Specificity Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver. {ECO:0000269|PubMed:15958283}.
Top Pathways Neurotrophin signaling pathway

Human NAD Synthetase full length protein - ab163006 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163006 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human NAD Synthetase protein fragment - ab163007 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163007 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human NADE peptide - ab39793 from Abcam

Category Peptide
Species Human

Human NADE protein fragment - ab132232 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE stained with Coomassie Blue showing ab132232.

Human NADE protein fragment - ab162056 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162056 on a 12.5% SDS-PAGE stained with Coomassie Blue.

NGFRAP1 / NADE / Bex Antibody Blocking Peptide - LS-E5526 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NGFRAP1 / NADE / Bex Antibody Blocking Peptide - LS-E30082 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

NGFRAP1 / NADE / Bex Antibody Blocking Peptide - LS-E26395 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human NGFRAP1/BEX3/NADE Protein - H00027018-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human NGFRAP1/BEX3/NADE Protein - H00027018-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

NGFRAP1/BEX3/NADE Blocking Peptide - NBP1-77149PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human
Western Blot: NADE Peptide [NBP1-77149PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C

NGFRAP1-Antibody-N-term-Blocking-Peptide - BP18054a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

NADE blocking peptide - GTX88746-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Rat

Recombinant human protein BEX3 (OPCA00171) - OPCA00171 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Recombinant human protein BEX3 (OPCA01284) - OPCA01284 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human BEX3 protein - orb180359 from Biorbyt

Category Protein
Prices $408.00, $595.00, $1,904.00, $2,933.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Source HEK293
Species Human

Human NGFRAP1 protein - orb244404 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human NGFRAP1 protein - orb245942 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

NADE Peptide - AC21-1231-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

NADE / BEX3 - H00027018-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

NADE / BEX3 - H00027018-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

NADE / BEX3 - H00027018-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

NADE / BEX3 - H00027018-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

NADE / BEX3 Control Peptide - AP30573CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

NADE Peptide - 3359P from ProSci

Category Peptide
Species Human
Western blot analysis of NADE in Human brain cell lysates with NADE antibody at 1 μg/mL in the presence (A) or absence (B) of blocking peptide (3359P).
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