TOLLIP

Gene Symbol	TOLLIP
Entrez Gene	54472
Alt Symbol	IL-1RAcPIP
Species	Human
Gene Type	protein-coding
Description	toll interacting protein
Other Description	adapter protein|toll-interacting protein
Swissprots	Q9H9E6 Q9H0E2 Q9UJ69 B3KXC6
Accessions	EAX02433 EAX02434 EAX02435 Q9H0E2 AA861717 AB209541 BAD92778 AJ242972 CAB58118 AK022871 BAB14283 AK090850 BAG52240 AK096693 BAC04844 AK127123 BAG54438 AK315592 BAG37964 AL136835 CAB66769 AM393373 CAL38251 AY730683 AAX22229 BC004420 AAH04420 BC012057 AAH12057 BC018272 AAH18272 BX648136 CR533477 CAG38508 DB039994 DQ891802 ABM82728 DQ894986 ABM85912 XM_011520192 XP_011518494 NM_019009 NP_061882
Function	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin- ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851). {ECO:0000269|PubMed:11751856, ECO:0000269|PubMed:25042851}.
Subcellular Location	Cytoplasm {ECO:0000305}.
Top Pathways	Toll-like receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TOLLIP ELISA Kit (Sandwich ELISA) - LS-F9763 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Toll Interacting Protein (TOLLIP), Human, ELISA Kit - CSB-E14976h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Toll-interacting protein (TOLLIP), Human, ELISA Kit - E01T0723 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

TOLLIP (Human) IP-WB Antibody Pair - H00054472-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TOLLIP (Human) Matched Antibody Pair - H00054472-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

toll interacting protein, ELISA Kit - MBS705405 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

Toll Interacting Protein (TOLLIP), ELISA Kit - MBS2024600 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of TOLLIP is typically less than 0.063ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Toll interacting protein (TOLLIP), ELISA Kit - MBS7206818 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7226401 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7205426 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7253384 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7219116 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7245772 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7251426 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7219943 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7249386 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Toll-interacting protein (TOLLIP), ELISA Kit - MBS7247100 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Toll Interacting Protein (TOLLIP) - SEC803Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL.. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Toll Interacting Protein (TOLLIP) ELISA Kit - CSB-E14976h from Cusabio Category ELISA Kit Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

ELISA Kit for Toll Interacting Protein (TOLLIP) - SEC803Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL.. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human TOLLIP ELISA Kit - abx153350 from Abbexa Category ELISA Kit Sensitivity 0.063 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human TOLLIP ELISA Kit - E038521 from Biobool Category ELISA Kit Sensitivity 4.68 pg/ml

TOLLIP ELISA Kit (Human) (OKCD00352) - OKCD00352 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.058 ng/mL Range 0.156-10 ng/mL

anti-Tollip antibody - ARG56416 from Arigo Biolaboratories Category ELISA Kit

anti-Tollip antibody [k1B17] - ARG56967 from Arigo Biolaboratories Category ELISA Kit

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