ITGA8

Gene Symbol	ITGA8
Entrez Gene	8516
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 8
Other Description	integrin alpha-8
Swissprots	Q5VX94 B0YJ31 P53708
Accessions	AAQ56848 ACA06009 EAW86235 P53708 AK297740 BAG60090 AK308240 BC148352 AAI48353 BU735798 DB237365 DC425586 L36531 AAA93514 XM_011519752 XP_011518054 NM_001291494 NP_001278423 NM_003638 NP_003629
Function	Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. {ECO:0000269|PubMed:12415008, ECO:0000269|PubMed:15721307}.
Subcellular Location	Membrane {ECO:0000269|PubMed:24439109}; Single-pass type I membrane protein {ECO:0000269|PubMed:24439109}. Cell membrane {ECO:0000269|PubMed:24439109}.
Tissue Specificity	Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level). {ECO:0000269|PubMed:10504498, ECO:0000269|PubMed:7768999}.
Top Pathways	Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Integrin alpha 8 (NP_003629) VersaClone cDNA - RDC0494 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Human ITGA8 cDNA clone(NM_003638.1) - CDFH009434 from Creative Biomart Species Human Accession NM_003638.1

Human ITGA8 ORF Clone(NM_003638.1) - CDCR286097 from Creative Biomart Species Human Accession NM_003638.1

Human ITGA8 ORF Clone(NM_003638.1) - CDCR286098 from Creative Biomart Species Human Accession NM_003638.1

Human ITGA8 ORF clone(NM_003638.1) - CDCH387376 from Creative Biomart Species Human Accession NM_003638.1

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone in cloning vector - HG12128-M from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12128-ACR from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, C-His tag - HG12128-CH from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12128-NF from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12128-NM from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12128-CF from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12128-ACG from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12128-CM from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12128-CY from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid - HG12128-UT from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12128-NY from Sino Biological Species Human

Human Integrin alpha 8/ITGA8 Gene ORF cDNA clone expression plasmid, N-His tag - HG12128-NH from Sino Biological Species Human

Mouse Integrin alpha 8 (NP_001001309) VersaClone cDNA - RDC1484 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

Human Integrin alpha 8 ORF clone(NM_003638.1) - CDCL184939 from Creative biogene Species Human

Human ITGA8 cDNA Clone(NM_003638.1) - CDFH009434 from Creative biogene Species Human

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