ITGA8

Gene Symbol	ITGA8
Entrez Gene	8516
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 8
Other Description	integrin alpha-8
Swissprots	Q5VX94 B0YJ31 P53708
Accessions	AAQ56848 ACA06009 EAW86235 P53708 AK297740 BAG60090 AK308240 BC148352 AAI48353 BU735798 DB237365 DC425586 L36531 AAA93514 XM_011519752 XP_011518054 NM_001291494 NP_001278423 NM_003638 NP_003629
Function	Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. {ECO:0000269|PubMed:12415008, ECO:0000269|PubMed:15721307}.
Subcellular Location	Membrane {ECO:0000269|PubMed:24439109}; Single-pass type I membrane protein {ECO:0000269|PubMed:24439109}. Cell membrane {ECO:0000269|PubMed:24439109}.
Tissue Specificity	Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level). {ECO:0000269|PubMed:10504498, ECO:0000269|PubMed:7768999}.
Top Pathways	Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ITGA8 protein fragment - ab160069 from Abcam Category Protein Source Wheat germ Species Human

ITGA8 / Integrin Alpha 8 Antibody Blocking Peptide - LS-E1089 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ITGA8 / Integrin Alpha 8 Antibody Blocking Peptide - LS-E16621 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Integrin alpha 8 Protein - H00008516-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ITGA8-Antibody-C-term-Blocking-peptide - BP11582b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ITGA8-Antibody-Center-Blocking-Peptide - BP14177c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ITGA8 flag His tag protein - orb84481 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source Human Species Human

Integrin alpha-8 / ITGA8 - H00008516-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Integrin alpha-8 / ITGA8 - H00008516-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human ITGA8, flag & His tagged - ITGA8-4118H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Integrin Alpha 8 (ITGa8) - RPC094Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Human ITGA8 & ITGB1 Heterodimer Protein - CT016-H2508H-20 from Sino Biological Category Protein Prices $138.00, $298.00 Sizes 20 µg, 50 µg Source Human Cells Species Human

Integrin alpha 8 HC Blocking Peptide - CBP4038 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

Recombinant Human Integrin alpha-8(ITGA8) ,partial - CSB-YP011871HU CSB-EP011871HU CSB-BP011871HU CSB-MP011871HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Integrin alpha-8 / ITGA8 - TP318936 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human ITGA8 & ITGB1 Heterodimer Protein - PKSH030482 from Elabscience Category Protein Source Human Cell Species Human

Integrin alpha 8 HC Blocking Peptide - abx162531 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Integrin alpha 8 Recombinant Protein Antigen - NBP1-86519PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ITGA8 Peptide, Human - M34GP07793H from Creative Peptides Category Peptide Source Synthetic. Species Human

ITGA8 Recombinant Protein (OPCD04570) - OPCD04570 from Aviva Systems Biology Category Protein Source E.coli Species Human

Integrin alpha-8 (ITGA8), partial, Recombinant Protein - MBS950821 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ITGA8 & ITGB1 Heterodimer, Recombinant Protein - MBS2545178 from MyBioSource Category Protein Prices $375.00, $775.00 Sizes 20 µg, 50 µg Source Human Cells

Search more