ITGA8

Gene Symbol	ITGA8
Entrez Gene	8516
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 8
Other Description	integrin alpha-8
Swissprots	Q5VX94 B0YJ31 P53708
Accessions	AAQ56848 ACA06009 EAW86235 P53708 AK297740 BAG60090 AK308240 BC148352 AAI48353 BU735798 DB237365 DC425586 L36531 AAA93514 XM_011519752 XP_011518054 NM_001291494 NP_001278423 NM_003638 NP_003629
Function	Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. {ECO:0000269|PubMed:12415008, ECO:0000269|PubMed:15721307}.
Subcellular Location	Membrane {ECO:0000269|PubMed:24439109}; Single-pass type I membrane protein {ECO:0000269|PubMed:24439109}. Cell membrane {ECO:0000269|PubMed:24439109}.
Tissue Specificity	Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level). {ECO:0000269|PubMed:10504498, ECO:0000269|PubMed:7768999}.
Top Pathways	Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Integrin α8 (F-11) - sc-365798 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Integrin α8 (F-19) - sc-30983 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Integrin α8 (T-20) - sc-6601 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Integrin α8 (H-180) - sc-25713 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Integrin α8 (S-16) - sc-30985 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-ITGA8 antibody - ab56355 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-ITGA8 antibody - ab106322 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 antibody - C-terminal - ab170464 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1025-1053) - LS-C165317 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa38-1007) - LS-C36922 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (Biotin) - LS-C70777 from LifeSpan Bioscience Prices $650.00 Sizes 50 µg Host Goat Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa610-800, PE) - LS-C130070 from LifeSpan Bioscience Prices $530.00 Sizes 100 tst Host Mouse Clonality Monoclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa610-800, APC) - LS-C130071 from LifeSpan Bioscience Prices $590.00 Sizes 100 tst Host Mouse Clonality Monoclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa38-1007) - LS-C150210 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061, AP) - LS-C260490 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061, APC) - LS-C260491 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061, Biotin) - LS-C260492 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061, FITC) - LS-C260493 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061, Azide-free, HRP) - LS-C260494 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061, PE) - LS-C260495 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa836-936) - LS-C308541 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa1032-1061) - LS-C329699 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ITGA8 / Integrin Alpha 8 Antibody (aa251-300) - LS-C111040 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Integrin alpha 8 Antibody (481709) [Unconjugated] - MAB6194 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 481709

Integrin alpha 8 Antibody - NBP1-59940 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

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