Gene Symbol | TFCP2 |
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Entrez Gene | 7024 |
Alt Symbol | LBP1C, LSF, LSF1D, SEF, TFCP2C |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor CP2 |
Other Description | SAA3 enhancer factor|alpha-globin transcription factor CP2 |
Swissprots | Q12800 A8K5E9 Q9UD77 Q12801 Q9UD75 |
Accessions | AAB29976 EAW58174 EAW58175 EAW58176 EAW58177 EAW58178 Q12800 AK291264 BAF83953 AK308087 AU133131 BC003634 AAH03634 BX479302 M84810 U03494 AAA21324 U03495 AAA21325 NM_001173452 NP_001166923 NM_001173453 NP_001166924 NM_005653 NP_005644 |
Function | Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. {ECO:0000250, ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:1732747, ECO:0000269|PubMed:8035790, ECO:0000269|PubMed:8157699}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:1732747, ECO:0000269|PubMed:7828600, ECO:0000269|PubMed:8114710}. |
Tissue Specificity | Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level). {ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:7828600, ECO:0000269|PubMed:8157699}. |
Human-TFCP2-cDNA-Clone - DC01361 from Abgent, a WuXi AppTec company
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TFCP2 - MBS1272615 from MyBioSource
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Human TFCP2 cDNA clone(NM_001173452.1) - CDFH019483 from Creative Biomart
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Human TFCP2 cDNA clone(NM_001173453.1) - CDFH019484 from Creative Biomart
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Human TFCP2 ORF Clone(NM_001173452.1) - CDCR356733 from Creative Biomart
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Human TFCP2 ORF Clone(NM_001173452.1) - CDCR356734 from Creative Biomart
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Human TFCP2 ORF Clone(NM_001173453.1) - CDCR356736 from Creative Biomart
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Human TFCP2 ORF Clone(NM_001173453.1) - CDCR356740 from Creative Biomart
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human TFCP2 ORF clone - CDCH090434 from Creative Biomart
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human TFCP2 ORF clone - CDCH090435 from Creative Biomart
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human TFCP2 ORF clone - CDCH090436 from Creative Biomart
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human TFCP2 ORF clone - CDCH090437 from Creative Biomart
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human TFCP2 ORF clone - CDCH090438 from Creative Biomart
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human TFCP2 ORF clone - CDCH090439 from Creative Biomart
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Human TFCP2 ORF Clone(NM_001173452.1) - CDCL178282 from Creative Biomart
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Human TFCP2 ORF Clone(NM_001173452.1) - CDCL178283 from Creative Biomart
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human TFCP2 ORF clone (NM_001173453.1) - CDCH090434 from Creative biogene
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human TFCP2 ORF clone (NM_001173452.1) - CDCH090436 from Creative biogene
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Human TFCP2 ORF Clone (BC003634) - CDCS409033 from Creative biogene
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Human TFCP2 cDNA Clone(NM_001173452.1) - CDFH019483 from Creative biogene
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Human TFCP2 cDNA Clone(NM_001173453.1) - CDFH019484 from Creative biogene
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