Gene Symbol | TFCP2 |
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Entrez Gene | 7024 |
Alt Symbol | LBP1C, LSF, LSF1D, SEF, TFCP2C |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor CP2 |
Other Description | SAA3 enhancer factor|alpha-globin transcription factor CP2 |
Swissprots | Q12800 A8K5E9 Q9UD77 Q12801 Q9UD75 |
Accessions | AAB29976 EAW58174 EAW58175 EAW58176 EAW58177 EAW58178 Q12800 AK291264 BAF83953 AK308087 AU133131 BC003634 AAH03634 BX479302 M84810 U03494 AAA21324 U03495 AAA21325 NM_001173452 NP_001166923 NM_001173453 NP_001166924 NM_005653 NP_005644 |
Function | Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. {ECO:0000250, ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:1732747, ECO:0000269|PubMed:8035790, ECO:0000269|PubMed:8157699}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:1732747, ECO:0000269|PubMed:7828600, ECO:0000269|PubMed:8114710}. |
Tissue Specificity | Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level). {ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:7828600, ECO:0000269|PubMed:8157699}. |
LBP-1C (P-14) - sc-168411 from Santa Cruz Biotechnology
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Anti-CP2c antibody - ab192426 from Abcam
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Anti-CP2c antibody - ab57750 from Abcam
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Anti-CP2c antibody [37] - ab178550 from Abcam
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Anti-TFCP2 / CP2 Antibody (aa310-335) - LS-C190105 from LifeSpan Bioscience
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Anti-TFCP2 / CP2 Antibody - LS-C341653 from LifeSpan Bioscience
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Anti-TFCP2 / CP2 Antibody (aa38-87) - LS-C79954 from LifeSpan Bioscience
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Anti-TFCP2 / CP2 Antibody - LS-C335581 from LifeSpan Bioscience
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Anti-TFCP2 / CP2 Antibody (clone 3H6) - LS-C198329 from LifeSpan Bioscience
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TFCP2 Antibody - H00007024-B01P from Novus Biologicals
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TFCP2 Antibody - H00007024-D01P from Novus Biologicals
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TFCP2 Antibody - NBP2-14917 from Novus Biologicals
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TFCP2 Antibody - H00007024-A01 from Novus Biologicals
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TFCP2 Antibody (3H6) - H00007024-M01 from Novus Biologicals
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TFCP2 Antibody - H00007024-D01 from Novus Biologicals
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TFCP2C Polyclonal Antibody - bs-9852R from Bioss
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Monoclonal Anti-TFCP2 antibody produced in mouse - WH0007024M1 from Sigma-Aldrich
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Anti-TFCP2 antibody produced in rabbit - AV31073 from Sigma-Aldrich
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Anti-TFCP2 antibody produced in rabbit - SAB1411340 from Sigma-Aldrich
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TFCP2 antibody - N-terminal region (ARP31073_P050) - ARP31073_P050 from Aviva Systems Biology
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TFCP2-Antibody-monoclonal-M01 - AT4216a from Abgent, a WuXi AppTec company
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TFCP2 Polyclonal Antibody - A5555 from ABclonal
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TFCP2 antibody - 70R-20780 from Fitzgerald
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TFCP2 Antibody - abx018345 from Abbexa
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TFCP2 Antibody - abx004254 from Abbexa
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