Gene Symbol | TFCP2 |
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Entrez Gene | 7024 |
Alt Symbol | LBP1C, LSF, LSF1D, SEF, TFCP2C |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor CP2 |
Other Description | SAA3 enhancer factor|alpha-globin transcription factor CP2 |
Swissprots | Q12800 A8K5E9 Q9UD77 Q12801 Q9UD75 |
Accessions | AAB29976 EAW58174 EAW58175 EAW58176 EAW58177 EAW58178 Q12800 AK291264 BAF83953 AK308087 AU133131 BC003634 AAH03634 BX479302 M84810 U03494 AAA21324 U03495 AAA21325 NM_001173452 NP_001166923 NM_001173453 NP_001166924 NM_005653 NP_005644 |
Function | Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. {ECO:0000250, ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:1732747, ECO:0000269|PubMed:8035790, ECO:0000269|PubMed:8157699}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:1732747, ECO:0000269|PubMed:7828600, ECO:0000269|PubMed:8114710}. |
Tissue Specificity | Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level). {ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:7828600, ECO:0000269|PubMed:8157699}. |
Human CP2c full length protein - ab159678 from Abcam
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Human CP2c protein fragment - ab159679 from Abcam
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TFCP2 / CP2 Antibody Blocking Peptide - LS-E10813 from LifeSpan Bioscience
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TFCP2 Recombinant Protein - H00007024-P01 from Novus Biologicals
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Recombinant Human TFCP2 Protein - H00007024-Q01 from Novus Biologicals
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TFCP2 - H00007024-P01 from Acris Antibodies
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TFCP2 - H00007024-Q01-10 from Acris Antibodies
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TFCP2 - H00007024-Q01-25 from Acris Antibodies
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TFCP2 fusion protein - Ag7521 from Proteintech Group
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TFCP2 fusion protein - Ag7353 from Proteintech Group
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Recombinant TFCP2 protein - 31250 from ActiveMotif
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Recombinant Human TFCP2, His-tagged - TFCP2-3196H from Creative Biomart
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Recombinant Human Alpha-globin transcription factor CP2(TFCP2) - CSB-YP621517HU CSB-EP621517HU CSB-BP621517HU CSB-MP621517HU from Cusabio
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Alpha-globin transcription factor CP2 (TFCP2) - MBS1434283 from MyBioSource
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TFCP2-Blocking-Peptide-Center - BP21657c from Abgent, a WuXi AppTec company
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TFCP2 Peptide, Human - M34GP15840H from Creative Peptides
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TFCP2 Recombinant Protein Antigen - NBP2-55972PEP from Novus Biologicals
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